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Results of arthroscopic treatment of chondral delamination in femoroacetabular impingement with bone marrow stimulation and BST-CarGel(®)

Objectives: The purpose of this study is to show the preliminary results of using chitosan-based scaffold (BST-CarGel(®)) with microfracture for treatment of acetabular chondral delamination associated with femoroacetabular impingement. Methods: A prospective study was performed on 13 hips. Patients...

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Autores principales: Tahoun, Mahmoud, Shehata, Tamer Aly, Ormazabal, Inmaculada, Mas, Jesús, Sanz, Javier, Tey Pons, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545970/
https://www.ncbi.nlm.nih.gov/pubmed/28782498
http://dx.doi.org/10.1051/sicotj/2017031
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author Tahoun, Mahmoud
Shehata, Tamer Aly
Ormazabal, Inmaculada
Mas, Jesús
Sanz, Javier
Tey Pons, Marc
author_facet Tahoun, Mahmoud
Shehata, Tamer Aly
Ormazabal, Inmaculada
Mas, Jesús
Sanz, Javier
Tey Pons, Marc
author_sort Tahoun, Mahmoud
collection PubMed
description Objectives: The purpose of this study is to show the preliminary results of using chitosan-based scaffold (BST-CarGel(®)) with microfracture for treatment of acetabular chondral delamination associated with femoroacetabular impingement. Methods: A prospective study was performed on 13 hips. Patients were selected in the age group between 18 and 50 years. Patients with delamination of acetabular cartilage associated with femoroacetabular impingement received arthroscopic debridement and microfracture technique. Then cases with defect > 2 cm(2) were considered for the application of BST-CarGel(®) and included in the study. Also, reattachment of the torn labrum and resection of the cam deformity were performed according to the case. For evaluation of the functional outcome, the patients had completed the hip outcome score (HOS) pre- and post-operatively. For evaluation of the regeneration of the cartilage, delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) was used and the percentage of defect filling and type of cartilage studied. Results: Patients had a mean age of 41 years, with moderate to high level of activity (mean Tegner scale 7). The mean size of the chondral defect after debridement was 3.7 cm(2). The mean HOS for daily live activities has been improved from 64.4 to 87.4 and for sports subscale from 35.2 to 75.2, which is statistically highly significant. All patients had > 90% of filling of chondral defect. Conclusion: The use of BST-CarGel(®) with microfracture for treatment of acetabular chondral delamination associated with femoroacetabular impingement can improve the functional outcome at two years, with a complete restoration of the cartilage defect in magnetic resonance images (MRI) with specific cartilage sequences.
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spelling pubmed-55459702017-08-24 Results of arthroscopic treatment of chondral delamination in femoroacetabular impingement with bone marrow stimulation and BST-CarGel(®) Tahoun, Mahmoud Shehata, Tamer Aly Ormazabal, Inmaculada Mas, Jesús Sanz, Javier Tey Pons, Marc SICOT J Original Article Objectives: The purpose of this study is to show the preliminary results of using chitosan-based scaffold (BST-CarGel(®)) with microfracture for treatment of acetabular chondral delamination associated with femoroacetabular impingement. Methods: A prospective study was performed on 13 hips. Patients were selected in the age group between 18 and 50 years. Patients with delamination of acetabular cartilage associated with femoroacetabular impingement received arthroscopic debridement and microfracture technique. Then cases with defect > 2 cm(2) were considered for the application of BST-CarGel(®) and included in the study. Also, reattachment of the torn labrum and resection of the cam deformity were performed according to the case. For evaluation of the functional outcome, the patients had completed the hip outcome score (HOS) pre- and post-operatively. For evaluation of the regeneration of the cartilage, delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) was used and the percentage of defect filling and type of cartilage studied. Results: Patients had a mean age of 41 years, with moderate to high level of activity (mean Tegner scale 7). The mean size of the chondral defect after debridement was 3.7 cm(2). The mean HOS for daily live activities has been improved from 64.4 to 87.4 and for sports subscale from 35.2 to 75.2, which is statistically highly significant. All patients had > 90% of filling of chondral defect. Conclusion: The use of BST-CarGel(®) with microfracture for treatment of acetabular chondral delamination associated with femoroacetabular impingement can improve the functional outcome at two years, with a complete restoration of the cartilage defect in magnetic resonance images (MRI) with specific cartilage sequences. EDP Sciences 2017-08-07 /pmc/articles/PMC5545970/ /pubmed/28782498 http://dx.doi.org/10.1051/sicotj/2017031 Text en © The Authors, published by EDP Sciences, 2017 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Tahoun, Mahmoud
Shehata, Tamer Aly
Ormazabal, Inmaculada
Mas, Jesús
Sanz, Javier
Tey Pons, Marc
Results of arthroscopic treatment of chondral delamination in femoroacetabular impingement with bone marrow stimulation and BST-CarGel(®)
title Results of arthroscopic treatment of chondral delamination in femoroacetabular impingement with bone marrow stimulation and BST-CarGel(®)
title_full Results of arthroscopic treatment of chondral delamination in femoroacetabular impingement with bone marrow stimulation and BST-CarGel(®)
title_fullStr Results of arthroscopic treatment of chondral delamination in femoroacetabular impingement with bone marrow stimulation and BST-CarGel(®)
title_full_unstemmed Results of arthroscopic treatment of chondral delamination in femoroacetabular impingement with bone marrow stimulation and BST-CarGel(®)
title_short Results of arthroscopic treatment of chondral delamination in femoroacetabular impingement with bone marrow stimulation and BST-CarGel(®)
title_sort results of arthroscopic treatment of chondral delamination in femoroacetabular impingement with bone marrow stimulation and bst-cargel(®)
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545970/
https://www.ncbi.nlm.nih.gov/pubmed/28782498
http://dx.doi.org/10.1051/sicotj/2017031
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