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Real-Life Management of Patients with Retinal Vein Occlusion Using I-Macula Web Platform

AIM: Real-life evaluation in the management of patients affected by macular edema secondary to retinal vein occlusion. MATERIAL AND METHODS: A retrospective, observational study using the I-Macula Web platform. RESULTS: Thirty-five patients (37 eyes; 15 females and 20 male) affected by RVO were anal...

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Autores principales: Nicolò, Massimo, Bonetto, Monica, Rosa, Raffaella, Musetti, Donatella, Musolino, Maria, Traverso, Carlo Enrico, Giacomini, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546074/
https://www.ncbi.nlm.nih.gov/pubmed/28811936
http://dx.doi.org/10.1155/2017/5601786
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author Nicolò, Massimo
Bonetto, Monica
Rosa, Raffaella
Musetti, Donatella
Musolino, Maria
Traverso, Carlo Enrico
Giacomini, Mauro
author_facet Nicolò, Massimo
Bonetto, Monica
Rosa, Raffaella
Musetti, Donatella
Musolino, Maria
Traverso, Carlo Enrico
Giacomini, Mauro
author_sort Nicolò, Massimo
collection PubMed
description AIM: Real-life evaluation in the management of patients affected by macular edema secondary to retinal vein occlusion. MATERIAL AND METHODS: A retrospective, observational study using the I-Macula Web platform. RESULTS: Thirty-five patients (37 eyes; 15 females and 20 male) affected by RVO were analysed. At 12 months, there was a statistically significant improvement of best-corrected visual acuity (p = 0.0235) and central macular thickness (p < 0.0001). The mean change in visual acuity was 8.9 letters. Twenty-seven eyes underwent DEX implant (n = 62; mean: 2.29) only. Of these, 8, 4, 14, and 1 eyes underwent 1, 2, 3, and 4 DEX implants, respectively. The remaining 10 eyes were also injected with ranibizumab (n = 49; mean: 4.9). At 12 months, 12 eyes (32.5%) presented a dry macula, whereas the remaining 25 eyes (67.5%) still had macular edema. Mean interval between the first and second treatment (T1) and between the second and third treatment (T2) were 5.15 and (T2) 3.7 months, respectively. Where only DEX implants were received, T1 and T2 was 5.1 and 4.9 months, respectively. CONCLUSIONS: This study confirms that DEX implants and/or anti-VEGF drugs improve visual acuity and central macular thickness in patients affected by RVO.
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spelling pubmed-55460742017-08-15 Real-Life Management of Patients with Retinal Vein Occlusion Using I-Macula Web Platform Nicolò, Massimo Bonetto, Monica Rosa, Raffaella Musetti, Donatella Musolino, Maria Traverso, Carlo Enrico Giacomini, Mauro J Ophthalmol Clinical Study AIM: Real-life evaluation in the management of patients affected by macular edema secondary to retinal vein occlusion. MATERIAL AND METHODS: A retrospective, observational study using the I-Macula Web platform. RESULTS: Thirty-five patients (37 eyes; 15 females and 20 male) affected by RVO were analysed. At 12 months, there was a statistically significant improvement of best-corrected visual acuity (p = 0.0235) and central macular thickness (p < 0.0001). The mean change in visual acuity was 8.9 letters. Twenty-seven eyes underwent DEX implant (n = 62; mean: 2.29) only. Of these, 8, 4, 14, and 1 eyes underwent 1, 2, 3, and 4 DEX implants, respectively. The remaining 10 eyes were also injected with ranibizumab (n = 49; mean: 4.9). At 12 months, 12 eyes (32.5%) presented a dry macula, whereas the remaining 25 eyes (67.5%) still had macular edema. Mean interval between the first and second treatment (T1) and between the second and third treatment (T2) were 5.15 and (T2) 3.7 months, respectively. Where only DEX implants were received, T1 and T2 was 5.1 and 4.9 months, respectively. CONCLUSIONS: This study confirms that DEX implants and/or anti-VEGF drugs improve visual acuity and central macular thickness in patients affected by RVO. Hindawi 2017 2017-07-24 /pmc/articles/PMC5546074/ /pubmed/28811936 http://dx.doi.org/10.1155/2017/5601786 Text en Copyright © 2017 Massimo Nicolò et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Nicolò, Massimo
Bonetto, Monica
Rosa, Raffaella
Musetti, Donatella
Musolino, Maria
Traverso, Carlo Enrico
Giacomini, Mauro
Real-Life Management of Patients with Retinal Vein Occlusion Using I-Macula Web Platform
title Real-Life Management of Patients with Retinal Vein Occlusion Using I-Macula Web Platform
title_full Real-Life Management of Patients with Retinal Vein Occlusion Using I-Macula Web Platform
title_fullStr Real-Life Management of Patients with Retinal Vein Occlusion Using I-Macula Web Platform
title_full_unstemmed Real-Life Management of Patients with Retinal Vein Occlusion Using I-Macula Web Platform
title_short Real-Life Management of Patients with Retinal Vein Occlusion Using I-Macula Web Platform
title_sort real-life management of patients with retinal vein occlusion using i-macula web platform
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546074/
https://www.ncbi.nlm.nih.gov/pubmed/28811936
http://dx.doi.org/10.1155/2017/5601786
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