Chronic diabetic states worsen Alzheimer neuropathology and cognitive deficits accompanying disruption of calcium signaling in leptin-deficient APP/PS1 mice

The coincidences between Alzheimer’s disease (AD) and type 2 diabetes mellitus (T2DM) are so compelling that it is attractive to speculate that diabetic conditions might aggravate AD pathologies by calcium dysfunction, although the understanding of the molecular mechanisms involved remains elusive....

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Detalles Bibliográficos
Autores principales: Zhang, Shuai, Chai, Rui, Yang, Ying-Ying, Guo, Shi-Qi, Wang, Shan, Guo, Tian, Xu, Shuang-Feng, Zhang, Yan-Hui, Wang, Zhan-You, Guo, Chuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546429/
https://www.ncbi.nlm.nih.gov/pubmed/28467789
http://dx.doi.org/10.18632/oncotarget.17116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546429/
https://www.ncbi.nlm.nih.gov/pubmed/28467789
http://dx.doi.org/10.18632/oncotarget.17116

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