U94 of human herpesvirus 6 down-modulates Src, promotes a partial mesenchymal-to-epithelial transition and inhibits tumor cell growth, invasion and metastasis

U94, the latency gene of human herpesvirus 6, was found to inhibit migration, invasion and proliferation of vascular endothelial cells (ECs). Because of its potent anti-migratory activity on ECs, we tested the capability of U94 to interfere with the individual steps of the metastatic cascade. We exa...

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Detalles Bibliográficos
Autores principales: Caccuri, Francesca, Ronca, Roberto, Laimbacher, Andrea S., Berenzi, Angiola, Steimberg, Nathalie, Campilongo, Federica, Mazzuca, Pietro, Giacomini, Arianna, Mazzoleni, Giovanna, Benetti, Anna, Caselli, Elisabetta, Presta, Marco, Luca, Dario Di, Fraefel, Cornel, Caruso, Arnaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546500/
https://www.ncbi.nlm.nih.gov/pubmed/28562350
http://dx.doi.org/10.18632/oncotarget.17817

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