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Ginkgolide K attenuates neuronal injury after ischemic stroke by inhibiting mitochondrial fission and GSK-3β-dependent increases in mitochondrial membrane permeability

Ginkgolide K (GK) belongs to the ginkgolide family of natural compounds found in Ginkgo biloba leaves, which have been used for centuries to treat cerebrovascular and cardiovascular diseases. We evaluated the protective effects of GK against neuronal apoptosis by assessing its ability to sustain mit...

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Detalles Bibliográficos
Autores principales: Zhou, Xu, Wang, Hui-Ying, Wu, Bin, Cheng, Cai-Yi, Xiao, Wei, Wang, Zhen-Zhong, Yang, Yu-Yu, Li, Ping, Yang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546510/
https://www.ncbi.nlm.nih.gov/pubmed/28591721
http://dx.doi.org/10.18632/oncotarget.17967