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Ginkgolide K attenuates neuronal injury after ischemic stroke by inhibiting mitochondrial fission and GSK-3β-dependent increases in mitochondrial membrane permeability
Ginkgolide K (GK) belongs to the ginkgolide family of natural compounds found in Ginkgo biloba leaves, which have been used for centuries to treat cerebrovascular and cardiovascular diseases. We evaluated the protective effects of GK against neuronal apoptosis by assessing its ability to sustain mit...
Autores principales: | Zhou, Xu, Wang, Hui-Ying, Wu, Bin, Cheng, Cai-Yi, Xiao, Wei, Wang, Zhen-Zhong, Yang, Yu-Yu, Li, Ping, Yang, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546510/ https://www.ncbi.nlm.nih.gov/pubmed/28591721 http://dx.doi.org/10.18632/oncotarget.17967 |
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