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Genome-wide methylome and chromatin interactome identify abnormal enhancer to be risk factor of breast cancer
Enhancer is critical cis regulatory elements in gene expression. To understand whether and how the aberrant enhancer activation may contribute to cancer risk, the differentially methylated enhancers (eDMRs) in normal and malignant breast tissues were identified and analyzed. By incorporating genome-...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546512/ https://www.ncbi.nlm.nih.gov/pubmed/28621677 http://dx.doi.org/10.18632/oncotarget.18348 |