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Catecholamines facilitate VEGF-dependent angiogenesis via β(2)-adrenoceptor-induced Epac1 and PKA activation

Chronic stress has been associated with the progression of cancer and antagonists for β-adrenoceptors (βAR) are regarded as therapeutic option. As they are also used to treat hemangiomas as well as retinopathy of prematurity, a role of endothelial β(2)AR in angiogenesis can be envisioned. We therefo...

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Detalles Bibliográficos
Autores principales: Garg, Jaspal, Feng, Yu-Xi, Jansen, Sepp R., Friedrich, Julian, Lezoualc'h, Frank, Schmidt, Martina, Wieland, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546514/
https://www.ncbi.nlm.nih.gov/pubmed/28512254
http://dx.doi.org/10.18632/oncotarget.17267