Cargando…

Deregulation of the non-coding genome in leukemia

Methodological advances that allow deeper characterization of non-coding elements in the genome have started to reveal the full spectrum of deregulation in cancer. We generated an inducible cell model to track transcriptional changes after induction of a well-known leukemia-inducing fusion gene, ETV...

Descripción completa

Detalles Bibliográficos
Autores principales:	Teppo, Susanna, Heinäniemi, Merja, Lohi, Olli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Point of View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546539/ https://www.ncbi.nlm.nih.gov/pubmed/28387584 http://dx.doi.org/10.1080/15476286.2017.1312228

Ejemplares similares

Non-coding RNAs, the cutting edge of histone messages
por: Köhn, Marcel, et al.
Publicado: (2016)

DUSP11 – An RNA phosphatase that regulates host and viral non-coding RNAs in mammalian cells
por: Burke, James M., et al.
Publicado: (2017)

Role of non-coding RNA transcription around gene regulatory elements in transcription factor recruitment
por: Takemata, Naomichi, et al.
Publicado: (2016)

Evolution of the genetic code
por: Lei, Lei, et al.
Publicado: (2021)

Might exogenous circular RNAs act as protein-coding transcripts in plants?
por: Marquez-Molins, Joan, et al.
Publicado: (2021)

Tyrosine-1 and threonine-4 phosphorylation marks complete the RNA polymerase II CTD phospho-code
por: Heidemann, Martin, et al.
Publicado: (2012)

Arginine Methyltransferase PRMT7 Deregulates Expression of RUNX1 Target Genes in T-Cell Acute Lymphoblastic Leukemia
por: Oksa, Laura, et al.
Publicado: (2022)

Proteome-wide analysis reveals clues of complementary interactions between mRNAs and their cognate proteins as the physicochemical foundation of the genetic code
por: Polyansky, Anton A, et al.
Publicado: (2013)

Perspectives of Fc engineered antibodies in CD19 targeting immunotherapies in pediatric B-cell precursor acute lymphoblastic leukemia
por: Kellner, Christian, et al.
Publicado: (2018)

Histone deacetylase complexes as caretakers of genome stability
por: Lahue, Robert, et al.
Publicado: (2012)

Genome-wide characterization of Mediator recruitment, function, and regulation
por: Grünberg, Sebastian, et al.
Publicado: (2017)

Genomic occupancy of the transcriptional co-activators p300 and CBP
por: Holmqvist, Per-Henrik, et al.
Publicado: (2013)

Circular RNAs with hammerhead ribozymes encoded in eukaryotic genomes: The enemy at home
por: de la Peña, Marcos, et al.
Publicado: (2017)

Bridging epigenetics and metabolism: Role of non-essential amino acids
por: Phang, James M., et al.
Publicado: (2013)

Transcription pausing: biological significance of thermal fluctuations biased by repetitive genomic sequences
por: Imashimizu, Masahiko, et al.
Publicado: (2017)

IGF2BP3 Associates with Proliferative Phenotype and Prognostic Features in B-Cell Acute Lymphoblastic Leukemia
por: Mäkinen, Artturi, et al.
Publicado: (2021)

Non-Health Subjects in Community Medicine: How Much Healthy or Medicinal are They?
por: Mohapatra, Sadhu Charan
Publicado: (2017)

Constitutional Proportionality in the Post-Non-Classical Scientific Paradigm and Modern Practice
por: Pashentsev, D. A.
Publicado: (2021)

Best Practices for Genomic Assay Testing in Early-Stage Breast Cancer: Clinical and Medicolegal Perspectives
por: Seidman, Andrew D., et al.
Publicado: (2017)

Non-native megaherbivores: the case for novel function to manage plant invasions on islands
por: Hansen, Dennis M.
Publicado: (2015)

Managing Non-COVID Acute Neurology Amidst the Pandemic: Challenges and Work in Progress
por: Gupta, Anu, et al.
Publicado: (2021)

“Genomic Homeopathy” proposal: use of auto-isotherapic of DNA as a modulator of gene expression in chronic diseases
Publicado: (2023)

Evolutionary aspects of plastid proteins involved in transcription: The transcription of a tiny genome is mediated by a complicated machinery
por: Yagi, Yusuke, et al.
Publicado: (2012)

Learning from nature: the use of non-model species to identify novel acclimations to flooding stress
por: Voesenek, L. A. C. J., et al.
Publicado: (2014)

Thymectomy in Non-Thymomatous Myasthenia Gravis: Does An RCT Solve The 75-Year-Old Controversy?
por: Singh, Nishita, et al.
Publicado: (2020)

Extraction of non-infected redundant pacing and defibrillator leads does not result in better patient outcomes
por: Bracke, Frank A., et al.
Publicado: (2023)

Perspectives on non-target site mechanisms of herbicide resistance in weedy plant species using evolutionary physiology
por: Ghanizadeh, Hossein, et al.
Publicado: (2017)

Human Vδ2 versus non-Vδ2 γδ T cells in antitumor immunity
por: Kabelitz, Dieter, et al.
Publicado: (2013)

SARS-CoV2 coronavirus: so far polite with children. Debatable immunological and non-immunological evidence
por: Álvez, F.
Publicado: (2020)

Border Zones of Evidence: How Non-evidence Based Factors Influence Evidence Generation and Clinical Practice in Stroke Medicine
por: Srijithesh, PR, et al.
Publicado: (2020)

Cytogenetics and Molecular Investigations detect a Mosaic Variant of Turner Syndrome only Suspected by Non-Invasive Prenatal Testing: Two Case Reports with Negative Ultrasound Examinations
por: Libotte, Francesco, et al.
Publicado: (2020)

Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots
por: Heinäniemi, Merja, et al.
Publicado: (2016)

Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia
por: Teppo, Susanna, et al.
Publicado: (2016)

Are Counseling Services Necessary for the Surgical Patients and their Family Members during Hospitalization?
por: Raju, Birudu, et al.
Publicado: (2017)

mTOR-sensitive translation: Cleared fog reveals more trees
por: Masvidal, Laia, et al.
Publicado: (2017)

ABCE1: A special factor that orchestrates translation at the crossroad between recycling and initiation
por: Mancera-Martínez, Eder, et al.
Publicado: (2017)

Insights into remodeling events during eukaryotic large ribosomal subunit assembly provided by high resolution cryo-EM structures
por: Biedka, Stephanie, et al.
Publicado: (2017)

Spontaneous Spinal Discitis and Spondylodiscitis: Clinicotherapeutic Remarks
por: Landi, Alessandro, et al.
Publicado: (2017)

Stroke risk in patients with device-detected atrial high-rate episodes
por: Erküner, Ö., et al.
Publicado: (2017)

The chemistries and consequences of DNA and RNA methylation and demethylation
por: Traube, Franziska R., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_fqsr819i5tdrcu7ccc8bpbr2ho