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MrTADFinder: A network modularity based approach to identify topologically associating domains in multiple resolutions

Genome-wide proximity ligation based assays such as Hi-C have revealed that eukaryotic genomes are organized into structural units called topologically associating domains (TADs). From a visual examination of the chromosomal contact map, however, it is clear that the organization of the domains is n...

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Detalles Bibliográficos
Autores principales: Yan, Koon-Kiu, Lou, Shaoke, Gerstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546724/
https://www.ncbi.nlm.nih.gov/pubmed/28742097
http://dx.doi.org/10.1371/journal.pcbi.1005647