Intracellular trafficking of new anticancer therapeutics: antibody–drug conjugates

Antibody–drug conjugate (ADC) is a milestone in targeted cancer therapy that comprises of monoclonal antibodies chemically linked to cytotoxic drugs. Internalization of ADC takes place via clathrin-mediated endocytosis, caveolae-mediated endocytosis, and pinocytosis. Conjugation strategies, endocyto...

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Detalles Bibliográficos
Autores principales: Kalim, Muhammad, Chen, Jie, Wang, Shenghao, Lin, Caiyao, Ullah, Saif, Liang, Keying, Ding, Qian, Chen, Shuqing, Zhan, Jinbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546728/
https://www.ncbi.nlm.nih.gov/pubmed/28814834
http://dx.doi.org/10.2147/DDDT.S135571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546728/
https://www.ncbi.nlm.nih.gov/pubmed/28814834
http://dx.doi.org/10.2147/DDDT.S135571

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