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Mutations in the C-terminus of HBoV NS1 affect the function of NP1

Human bocavirus 1 (HBoV1) is an autonomous parvovirus in the Bocaparvovirus genus. The multifunctional nuclear protein NP1 is involved in viral replication. In the present study, we found that the mutations in the C-terminus of NS1 affected NP1 function in viral replication. Knocking out NP1 express...

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Detalles Bibliográficos
Autores principales: Zhang, Junmei, Bai, Yan, Zhu, Bing, Hao, Sujuan, Chen, Zhen, Wang, Hanzhong, Guan, Wuxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547040/
https://www.ncbi.nlm.nih.gov/pubmed/28785044
http://dx.doi.org/10.1038/s41598-017-06513-4

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