Cargando…

Neural correlates of proactive and reactive motor response inhibition of gambling stimuli in frequent gamblers

We used functional magnetic resonance imaging to examine whether motivational-salient cues could exert a differential impact on proactive (the restrain of actions in preparation for stopping) and reactive (outright stopping) inhibition. Fourteen high-frequency poker players, and 14 matched non-gambl...

Descripción completa

Detalles Bibliográficos
Autores principales: Brevers, D., He, Q., Keller, B., Noël, X., Bechara, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547049/
https://www.ncbi.nlm.nih.gov/pubmed/28785029
http://dx.doi.org/10.1038/s41598-017-07786-5
_version_ 1783255639236018176
author Brevers, D.
He, Q.
Keller, B.
Noël, X.
Bechara, A.
author_facet Brevers, D.
He, Q.
Keller, B.
Noël, X.
Bechara, A.
author_sort Brevers, D.
collection PubMed
description We used functional magnetic resonance imaging to examine whether motivational-salient cues could exert a differential impact on proactive (the restrain of actions in preparation for stopping) and reactive (outright stopping) inhibition. Fourteen high-frequency poker players, and 14 matched non-gambler controls, performed a modified version of the stop-signal paradigm, which required participants to inhibit categorization of poker or neutral pictures. The probability that a stop-signal occurs (0%, 17%, 25%, 33%) was manipulated across blocks of trials, as indicated by the color of the computer screen. Behavioral analyses revealed that poker players were faster than controls in categorizing pictures across all levels of proactive motor response inhibition (go trials). Brain imaging analyses highlighted higher dorsal anterior cingulate cortex activation in poker players, as compared to controls, during reactive inhibition. These findings suggest that, due to their faster rates of stimulus discrimination, poker players might have recruited more cognitive resources than controls when required to stop their response (reactive inhibition). Nevertheless, no main effect of stimulus type was found, on either proactive or reactive inhibition. Additional studies are, therefore, needed in order to confirm that investigating the dynamics between reactive and proactive inhibition offers a discriminative analysis of inhibitory control toward motivational-salient cues.
format Online
Article
Text
id pubmed-5547049
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-55470492017-08-09 Neural correlates of proactive and reactive motor response inhibition of gambling stimuli in frequent gamblers Brevers, D. He, Q. Keller, B. Noël, X. Bechara, A. Sci Rep Article We used functional magnetic resonance imaging to examine whether motivational-salient cues could exert a differential impact on proactive (the restrain of actions in preparation for stopping) and reactive (outright stopping) inhibition. Fourteen high-frequency poker players, and 14 matched non-gambler controls, performed a modified version of the stop-signal paradigm, which required participants to inhibit categorization of poker or neutral pictures. The probability that a stop-signal occurs (0%, 17%, 25%, 33%) was manipulated across blocks of trials, as indicated by the color of the computer screen. Behavioral analyses revealed that poker players were faster than controls in categorizing pictures across all levels of proactive motor response inhibition (go trials). Brain imaging analyses highlighted higher dorsal anterior cingulate cortex activation in poker players, as compared to controls, during reactive inhibition. These findings suggest that, due to their faster rates of stimulus discrimination, poker players might have recruited more cognitive resources than controls when required to stop their response (reactive inhibition). Nevertheless, no main effect of stimulus type was found, on either proactive or reactive inhibition. Additional studies are, therefore, needed in order to confirm that investigating the dynamics between reactive and proactive inhibition offers a discriminative analysis of inhibitory control toward motivational-salient cues. Nature Publishing Group UK 2017-08-07 /pmc/articles/PMC5547049/ /pubmed/28785029 http://dx.doi.org/10.1038/s41598-017-07786-5 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Brevers, D.
He, Q.
Keller, B.
Noël, X.
Bechara, A.
Neural correlates of proactive and reactive motor response inhibition of gambling stimuli in frequent gamblers
title Neural correlates of proactive and reactive motor response inhibition of gambling stimuli in frequent gamblers
title_full Neural correlates of proactive and reactive motor response inhibition of gambling stimuli in frequent gamblers
title_fullStr Neural correlates of proactive and reactive motor response inhibition of gambling stimuli in frequent gamblers
title_full_unstemmed Neural correlates of proactive and reactive motor response inhibition of gambling stimuli in frequent gamblers
title_short Neural correlates of proactive and reactive motor response inhibition of gambling stimuli in frequent gamblers
title_sort neural correlates of proactive and reactive motor response inhibition of gambling stimuli in frequent gamblers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547049/
https://www.ncbi.nlm.nih.gov/pubmed/28785029
http://dx.doi.org/10.1038/s41598-017-07786-5
work_keys_str_mv AT breversd neuralcorrelatesofproactiveandreactivemotorresponseinhibitionofgamblingstimuliinfrequentgamblers
AT heq neuralcorrelatesofproactiveandreactivemotorresponseinhibitionofgamblingstimuliinfrequentgamblers
AT kellerb neuralcorrelatesofproactiveandreactivemotorresponseinhibitionofgamblingstimuliinfrequentgamblers
AT noelx neuralcorrelatesofproactiveandreactivemotorresponseinhibitionofgamblingstimuliinfrequentgamblers
AT becharaa neuralcorrelatesofproactiveandreactivemotorresponseinhibitionofgamblingstimuliinfrequentgamblers