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Knockdown of Tlr4 in the Arcuate Nucleus Improves Obesity Related Metabolic Disorders

High-fat diet-induced hypothalamic metabolic inflammation is emerging as a cause for the development of obesity. It is acknowledged that Toll-like receptor4 (TLR4) signaling plays a crucial role in triggering of the hypothalamic metabolic inflammation during the course of diet-induced obesity. Wheth...

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Detalles Bibliográficos
Autores principales: Zhao, Yongli, Li, Guohua, Li, Ying, Wang, Yuchuan, Liu, Zhengjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547063/
https://www.ncbi.nlm.nih.gov/pubmed/28785099
http://dx.doi.org/10.1038/s41598-017-07858-6

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