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Knockdown of Tlr4 in the Arcuate Nucleus Improves Obesity Related Metabolic Disorders
High-fat diet-induced hypothalamic metabolic inflammation is emerging as a cause for the development of obesity. It is acknowledged that Toll-like receptor4 (TLR4) signaling plays a crucial role in triggering of the hypothalamic metabolic inflammation during the course of diet-induced obesity. Wheth...
Autores principales: | Zhao, Yongli, Li, Guohua, Li, Ying, Wang, Yuchuan, Liu, Zhengjuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547063/ https://www.ncbi.nlm.nih.gov/pubmed/28785099 http://dx.doi.org/10.1038/s41598-017-07858-6 |
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