MUC1-C activates EZH2 expression and function in human cancer cells

The EZH2 histone methyltransferase is a member of the polycomb repressive complex 2 (PRC2) that is highly expressed in diverse human cancers and is associated with a poor prognosis. MUC1-C is an oncoprotein that is similarly overexpressed in carcinomas and has been linked to epigenetic regulation. A...

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Detalles Bibliográficos
Autores principales: Rajabi, Hasan, Hiraki, Masayuki, Tagde, Ashujit, Alam, Maroof, Bouillez, Audrey, Christensen, Camilla L., Samur, Mehmet, Wong, Kwok-Kin, Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547076/
https://www.ncbi.nlm.nih.gov/pubmed/28785086
http://dx.doi.org/10.1038/s41598-017-07850-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547076/
https://www.ncbi.nlm.nih.gov/pubmed/28785086
http://dx.doi.org/10.1038/s41598-017-07850-0

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