A high-throughput chemical screen identifies novel inhibitors and enhancers of anti-inflammatory functions of the glucocorticoid receptor

Glucocorticoids (GCs)—ligands of the glucocorticoid receptor (GR)—are widely used to treat inflammatory diseases, but suffer from significant side effects and poor responsiveness in certain patient populations. Identification of chemical GR modulators may provide insights into the regulatory mechani...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaofeng, Dahlin, Amber, Weiss, Scott T., Tantisira, Kelan, Lu, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547123/
https://www.ncbi.nlm.nih.gov/pubmed/28785063
http://dx.doi.org/10.1038/s41598-017-07565-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547123/
https://www.ncbi.nlm.nih.gov/pubmed/28785063
http://dx.doi.org/10.1038/s41598-017-07565-2

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