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Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis

Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder resulting from mutations in the dystrophin gene. The mdx/utrn (−/−) mouse, lacking in both dystrophin and its autosomal homologue utrophin, is commonly used to model the clinical symptoms of DMD. Interestingly, these mice are infertil...

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Detalles Bibliográficos
Autores principales:	Chen, Hung-Chih, Chin, Yu-Feng, Lundy, David J., Liang, Chung-Tiang, Chi, Ya-Hui, Kuo, Paolin, Hsieh, Patrick C. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547154/ https://www.ncbi.nlm.nih.gov/pubmed/28785010 http://dx.doi.org/10.1038/s41598-017-05993-8

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