Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose

The data presented in this article are related to the research article entitled “Regulation of GLUT4 activity in myotubes by 3-O-methyl-D-glucose” (Shamni et al., 2017) [1]. These data show that the experimental procedures used to analyze the effects of 3-O-methyl-D-glucose (MeGlc) on the rate of he...

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Autores principales: Shamni, Ofer, Cohen, Guy, Gruzman, Arie, Zaid, Hilal, Klip, Amira, Cerasi, Erol, Sasson, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Genetics, Genomics and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547241/
https://www.ncbi.nlm.nih.gov/pubmed/28795110
http://dx.doi.org/10.1016/j.dib.2017.07.069
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author Shamni, Ofer
Cohen, Guy
Gruzman, Arie
Zaid, Hilal
Klip, Amira
Cerasi, Erol
Sasson, Shlomo
author_facet Shamni, Ofer
Cohen, Guy
Gruzman, Arie
Zaid, Hilal
Klip, Amira
Cerasi, Erol
Sasson, Shlomo
author_sort Shamni, Ofer
collection PubMed
description The data presented in this article are related to the research article entitled “Regulation of GLUT4 activity in myotubes by 3-O-methyl-D-glucose” (Shamni et al., 2017) [1]. These data show that the experimental procedures used to analyze the effects of 3-O-methyl-D-glucose (MeGlc) on the rate of hexose transport into myotubes were valid and controlled. The stimulatory effect of MeGlc was limited to glucose transporter 4 (GLUT4) and was independent of ambient glucose and protein synthesis. Cornish-Bowden kinetic analysis of uptake data revealed that MeGlc attenuated indinavir-induced inhibition of hexose transport in a competitive manner.
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spelling pubmed-55472412017-08-09 Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose Shamni, Ofer Cohen, Guy Gruzman, Arie Zaid, Hilal Klip, Amira Cerasi, Erol Sasson, Shlomo Data Brief Genetics, Genomics and Molecular Biology The data presented in this article are related to the research article entitled “Regulation of GLUT4 activity in myotubes by 3-O-methyl-D-glucose” (Shamni et al., 2017) [1]. These data show that the experimental procedures used to analyze the effects of 3-O-methyl-D-glucose (MeGlc) on the rate of hexose transport into myotubes were valid and controlled. The stimulatory effect of MeGlc was limited to glucose transporter 4 (GLUT4) and was independent of ambient glucose and protein synthesis. Cornish-Bowden kinetic analysis of uptake data revealed that MeGlc attenuated indinavir-induced inhibition of hexose transport in a competitive manner. Elsevier 2017-07-28 /pmc/articles/PMC5547241/ /pubmed/28795110 http://dx.doi.org/10.1016/j.dib.2017.07.069 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Genetics, Genomics and Molecular Biology
Shamni, Ofer
Cohen, Guy
Gruzman, Arie
Zaid, Hilal
Klip, Amira
Cerasi, Erol
Sasson, Shlomo
Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose
title Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose
title_full Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose
title_fullStr Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose
title_full_unstemmed Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose
title_short Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose
title_sort supportive data on the regulation of glut4 activity by 3-o-methyl-d-glucose
topic Genetics, Genomics and Molecular Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547241/
https://www.ncbi.nlm.nih.gov/pubmed/28795110
http://dx.doi.org/10.1016/j.dib.2017.07.069
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