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Anti-aging activities of extracts from Tunisian medicinal halophytes and their aromatic constituents

Six medicinal halophytes widely represented in North Africa and commonly used in traditional medicine were screened for pharmacological properties to set out new promising sources of natural ingredients for cosmetic or nutraceutical applications. Thus, Citrullus colocynthis, Cleome arabica, Daemia c...

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Autores principales: Jdey, A., Falleh, H., Ben Jannet, S., Mkadmini Hammi, K., Dauvergne, X., Magné, C., Ksouri, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547381/
https://www.ncbi.nlm.nih.gov/pubmed/28827992
http://dx.doi.org/10.17179/excli2017-244
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author Jdey, A.
Falleh, H.
Ben Jannet, S.
Mkadmini Hammi, K.
Dauvergne, X.
Magné, C.
Ksouri, R.
author_facet Jdey, A.
Falleh, H.
Ben Jannet, S.
Mkadmini Hammi, K.
Dauvergne, X.
Magné, C.
Ksouri, R.
author_sort Jdey, A.
collection PubMed
description Six medicinal halophytes widely represented in North Africa and commonly used in traditional medicine were screened for pharmacological properties to set out new promising sources of natural ingredients for cosmetic or nutraceutical applications. Thus, Citrullus colocynthis, Cleome arabica, Daemia cordata, Haloxylon articulatum, Pituranthos scoparius and Scorzonera undulata were examined for their in vitro antioxidant (DPPH scavenging and superoxide anion-scavenging, β-carotene bleaching inhibition and iron-reducing tests), antibacterial (microdilution method, against four human pathogenic bacteria) and anti-tyrosinase activities. Besides, their aromatic composition was determined by RP-HPLC. H. articulatum shoot extracts exhibited the strongest antioxidant activity and inhibited efficiently the growth of Salmonella enterica and Escherichia coli. P. scoparius and C. arabica inhibited slightly monophenolase, whereas H. articulatum was the most efficient inhibitor of diphenolase activity. Furthermore, H. articulatum exhibited the highest aromatic content (3.4 % DW), with dopamine as the major compound. These observations suggest that shoot extract of H. articulatum, and to a lesser extent of C. arabica, could be used as antioxidant, antibiotic as well as new natural skin lightening agents. Also, possible implication of aromatic compounds in anti-tyrosinase activity is discussed.
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spelling pubmed-55473812017-08-21 Anti-aging activities of extracts from Tunisian medicinal halophytes and their aromatic constituents Jdey, A. Falleh, H. Ben Jannet, S. Mkadmini Hammi, K. Dauvergne, X. Magné, C. Ksouri, R. EXCLI J Original Article Six medicinal halophytes widely represented in North Africa and commonly used in traditional medicine were screened for pharmacological properties to set out new promising sources of natural ingredients for cosmetic or nutraceutical applications. Thus, Citrullus colocynthis, Cleome arabica, Daemia cordata, Haloxylon articulatum, Pituranthos scoparius and Scorzonera undulata were examined for their in vitro antioxidant (DPPH scavenging and superoxide anion-scavenging, β-carotene bleaching inhibition and iron-reducing tests), antibacterial (microdilution method, against four human pathogenic bacteria) and anti-tyrosinase activities. Besides, their aromatic composition was determined by RP-HPLC. H. articulatum shoot extracts exhibited the strongest antioxidant activity and inhibited efficiently the growth of Salmonella enterica and Escherichia coli. P. scoparius and C. arabica inhibited slightly monophenolase, whereas H. articulatum was the most efficient inhibitor of diphenolase activity. Furthermore, H. articulatum exhibited the highest aromatic content (3.4 % DW), with dopamine as the major compound. These observations suggest that shoot extract of H. articulatum, and to a lesser extent of C. arabica, could be used as antioxidant, antibiotic as well as new natural skin lightening agents. Also, possible implication of aromatic compounds in anti-tyrosinase activity is discussed. Leibniz Research Centre for Working Environment and Human Factors 2017-05-22 /pmc/articles/PMC5547381/ /pubmed/28827992 http://dx.doi.org/10.17179/excli2017-244 Text en Copyright © 2017 Jdey et al. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/4.0/) You are free to copy, distribute and transmit the work, provided the original author and source are credited.
spellingShingle Original Article
Jdey, A.
Falleh, H.
Ben Jannet, S.
Mkadmini Hammi, K.
Dauvergne, X.
Magné, C.
Ksouri, R.
Anti-aging activities of extracts from Tunisian medicinal halophytes and their aromatic constituents
title Anti-aging activities of extracts from Tunisian medicinal halophytes and their aromatic constituents
title_full Anti-aging activities of extracts from Tunisian medicinal halophytes and their aromatic constituents
title_fullStr Anti-aging activities of extracts from Tunisian medicinal halophytes and their aromatic constituents
title_full_unstemmed Anti-aging activities of extracts from Tunisian medicinal halophytes and their aromatic constituents
title_short Anti-aging activities of extracts from Tunisian medicinal halophytes and their aromatic constituents
title_sort anti-aging activities of extracts from tunisian medicinal halophytes and their aromatic constituents
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547381/
https://www.ncbi.nlm.nih.gov/pubmed/28827992
http://dx.doi.org/10.17179/excli2017-244
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