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Evaluation and comparison of computational tools for RNA-seq isoform quantification

BACKGROUND: Alternatively spliced transcript isoforms are commonly observed in higher eukaryotes. The expression levels of these isoforms are key for understanding normal functions in healthy tissues and the progression of disease states. However, accurate quantification of expression at the transcr...

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Detalles Bibliográficos
Autores principales: Zhang, Chi, Zhang, Baohong, Lin, Lih-Ling, Zhao, Shanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547501/
https://www.ncbi.nlm.nih.gov/pubmed/28784092
http://dx.doi.org/10.1186/s12864-017-4002-1