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p27(Kip1 )is expressed in proliferating cells in its form phosphorylated on threonine 187
BACKGROUND: G1/S cell cycle progression requires p27(Kip1 )(p27) proteolysis, which is triggered by its phosphorylation on threonine (Thr) 187. Since its levels are abundant in quiescent and scarce in cycling cells, p27 is an approved marker for quiescent cells, extensively used in histopathology an...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC554775/ https://www.ncbi.nlm.nih.gov/pubmed/15725363 http://dx.doi.org/10.1186/1472-6890-5-3 |