Cargando…
p27(Kip1 )is expressed in proliferating cells in its form phosphorylated on threonine 187
BACKGROUND: G1/S cell cycle progression requires p27(Kip1 )(p27) proteolysis, which is triggered by its phosphorylation on threonine (Thr) 187. Since its levels are abundant in quiescent and scarce in cycling cells, p27 is an approved marker for quiescent cells, extensively used in histopathology an...
Autores principales: | Troncone, Giancarlo, Martinez, Juan C, Iaccarino, Antonino, Zeppa, Pio, Caleo, Alessia, Russo, Maria, Migliaccio, Ilenia, Motti, Maria L, Califano, Daniela, Palmieri, Emiliano A, Palombini, Lucio |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC554775/ https://www.ncbi.nlm.nih.gov/pubmed/15725363 http://dx.doi.org/10.1186/1472-6890-5-3 |
Ejemplares similares
-
Phosphorylation of p27(Kip1) at Thr187 by Cyclin-dependent Kinase 5 Modulates Neural Stem Cell Differentiation
por: Zheng, Ya-Li, et al.
Publicado: (2010) -
Regulation of p27(Kip1) and p57(Kip2) Functions by Natural Polyphenols
por: Russo, Gian Luigi, et al.
Publicado: (2020) -
Cytological and molecular diagnosis of solid variant of papillary thyroid carcinoma: A case report
por: Troncone, Giancarlo, et al.
Publicado: (2008) -
p27kip1 at the crossroad between actin and microtubule dynamics
por: Rampioni Vinciguerra, Gian Luca, et al.
Publicado: (2019) -
Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo
por: Berton, Stefania, et al.
Publicado: (2014)