mcr-1 and bla(KPC-3) in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal

Escherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-bla(KPC-3), already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene. Results highlight emerging co-resistance t...

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Detalles Bibliográficos
Autores principales: Tacão, Marta, Tavares, Rafael dos Santos, Teixeira, Pedro, Roxo, Inês, Ramalheira, Elmano, Ferreira, Sónia, Henriques, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547783/
https://www.ncbi.nlm.nih.gov/pubmed/28726622
http://dx.doi.org/10.3201/eid2308.170162
Descripción
Sumario:Escherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-bla(KPC-3), already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene. Results highlight emerging co-resistance to carbapenems and polymyxins after therapy with drugs from both classes.

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