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mcr-1 and bla(KPC-3) in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal

Escherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-bla(KPC-3), already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene. Results highlight emerging co-resistance t...

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Autores principales: Tacão, Marta, Tavares, Rafael dos Santos, Teixeira, Pedro, Roxo, Inês, Ramalheira, Elmano, Ferreira, Sónia, Henriques, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547783/
https://www.ncbi.nlm.nih.gov/pubmed/28726622
http://dx.doi.org/10.3201/eid2308.170162
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author Tacão, Marta
Tavares, Rafael dos Santos
Teixeira, Pedro
Roxo, Inês
Ramalheira, Elmano
Ferreira, Sónia
Henriques, Isabel
author_facet Tacão, Marta
Tavares, Rafael dos Santos
Teixeira, Pedro
Roxo, Inês
Ramalheira, Elmano
Ferreira, Sónia
Henriques, Isabel
author_sort Tacão, Marta
collection PubMed
description Escherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-bla(KPC-3), already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene. Results highlight emerging co-resistance to carbapenems and polymyxins after therapy with drugs from both classes.
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spelling pubmed-55477832017-08-08 mcr-1 and bla(KPC-3) in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal Tacão, Marta Tavares, Rafael dos Santos Teixeira, Pedro Roxo, Inês Ramalheira, Elmano Ferreira, Sónia Henriques, Isabel Emerg Infect Dis Research Letter Escherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-bla(KPC-3), already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene. Results highlight emerging co-resistance to carbapenems and polymyxins after therapy with drugs from both classes. Centers for Disease Control and Prevention 2017-08 /pmc/articles/PMC5547783/ /pubmed/28726622 http://dx.doi.org/10.3201/eid2308.170162 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Tacão, Marta
Tavares, Rafael dos Santos
Teixeira, Pedro
Roxo, Inês
Ramalheira, Elmano
Ferreira, Sónia
Henriques, Isabel
mcr-1 and bla(KPC-3) in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
title mcr-1 and bla(KPC-3) in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
title_full mcr-1 and bla(KPC-3) in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
title_fullStr mcr-1 and bla(KPC-3) in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
title_full_unstemmed mcr-1 and bla(KPC-3) in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
title_short mcr-1 and bla(KPC-3) in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
title_sort mcr-1 and bla(kpc-3) in escherichia coli sequence type 744 after meropenem and colistin therapy, portugal
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547783/
https://www.ncbi.nlm.nih.gov/pubmed/28726622
http://dx.doi.org/10.3201/eid2308.170162
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