Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia

In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used core-genome analysis to show emergence of a penicillin-resistant clade that had the penA_253 allele. This new penicillin-resistant clade might af...

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Autores principales: Mowlaboccus, Shakeel, Jolley, Keith A., Bray, James E., Pang, Stanley, Lee, Yung Thin, Bew, Jane D., Speers, David J., Keil, Anthony D., Coombs, Geoffrey W., Kahler, Charlene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547816/
https://www.ncbi.nlm.nih.gov/pubmed/28609259
http://dx.doi.org/10.3201/eid2308.170259
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author Mowlaboccus, Shakeel
Jolley, Keith A.
Bray, James E.
Pang, Stanley
Lee, Yung Thin
Bew, Jane D.
Speers, David J.
Keil, Anthony D.
Coombs, Geoffrey W.
Kahler, Charlene M.
author_facet Mowlaboccus, Shakeel
Jolley, Keith A.
Bray, James E.
Pang, Stanley
Lee, Yung Thin
Bew, Jane D.
Speers, David J.
Keil, Anthony D.
Coombs, Geoffrey W.
Kahler, Charlene M.
author_sort Mowlaboccus, Shakeel
collection PubMed
description In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used core-genome analysis to show emergence of a penicillin-resistant clade that had the penA_253 allele. This new penicillin-resistant clade might affect treatment regimens for this disease.
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spelling pubmed-55478162017-08-08 Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia Mowlaboccus, Shakeel Jolley, Keith A. Bray, James E. Pang, Stanley Lee, Yung Thin Bew, Jane D. Speers, David J. Keil, Anthony D. Coombs, Geoffrey W. Kahler, Charlene M. Emerg Infect Dis Dispatch In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used core-genome analysis to show emergence of a penicillin-resistant clade that had the penA_253 allele. This new penicillin-resistant clade might affect treatment regimens for this disease. Centers for Disease Control and Prevention 2017-08 /pmc/articles/PMC5547816/ /pubmed/28609259 http://dx.doi.org/10.3201/eid2308.170259 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Mowlaboccus, Shakeel
Jolley, Keith A.
Bray, James E.
Pang, Stanley
Lee, Yung Thin
Bew, Jane D.
Speers, David J.
Keil, Anthony D.
Coombs, Geoffrey W.
Kahler, Charlene M.
Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia
title Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia
title_full Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia
title_fullStr Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia
title_full_unstemmed Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia
title_short Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia
title_sort clonal expansion of new penicillin-resistant clade of neisseria meningitidis serogroup w clonal complex 11, australia
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547816/
https://www.ncbi.nlm.nih.gov/pubmed/28609259
http://dx.doi.org/10.3201/eid2308.170259
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