Cargando…

Paeoniflorin exerts neuroprotective effects against glutamate-induced PC12 cellular cytotoxicity by inhibiting apoptosis

Paeoniflorin (PF) is an active ingredient of Radix Paeoniae, which is known to exert neuroprotective effects. However, the mechanims behind the neuroprotective effects of PF are not yet fully understood. The apoptosis of neurons plays an important role in the cerebral ischemia-induced cascade respon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Ahong, Wang, Hongyun, Zhang, Yuqin, Wang, Xiaoying, Yu, Lishuang, Xu, Wen, Xu, Wei, Lin, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547935/ https://www.ncbi.nlm.nih.gov/pubmed/28731183 http://dx.doi.org/10.3892/ijmm.2017.3076

Ejemplares similares

Predicting a Potential Link to Antidepressant Effect: Neuroprotection of Zhi-zi-chi Decoction on Glutamate-induced Cytotoxicity in PC12 Cells
por: Zhang, Yin, et al.
Publicado: (2021)

Paeoniflorin Attenuates Cerebral Ischemia-Induced Injury by Regulating Ca(2+)/CaMKII/CREB Signaling Pathway
por: Zhang, Yuqin, et al.
Publicado: (2017)

Neuroprotective effects of 20(S)-protopanaxadiol against glutamate-induced mitochondrial dysfunction in PC12 cells
por: BAK, DONG-HO, et al.
Publicado: (2016)

The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer’s Disease Mouse Model
por: Zhang, Junrong, et al.
Publicado: (2016)

Methylprednisolone exerts neuroprotective effects by regulating autophagy and apoptosis
por: Gao, Wei, et al.
Publicado: (2016)

Therapeutic potential of paeoniflorin in atherosclerosis: A cellular action and mechanism-based perspective
por: Yu, Wei, et al.
Publicado: (2022)

Paeoniflorin exerts antitumor effects by inactivating S phase kinase-associated protein 2 in glioma cells
por: Ouyang, Jia, et al.
Publicado: (2018)

Longistyline C acts antidepressant in vivo and neuroprotection in vitro against glutamate-induced cytotoxicity by regulating NMDAR/NR2B-ERK pathway in PC12 cells
por: Liu, Yamin, et al.
Publicado: (2017)

Paeoniflorin inhibits proliferation and promotes autophagy and apoptosis of sweat gland cells
por: Xu, Yuan, et al.
Publicado: (2022)

Network pharmacology and in vivo studies reveal the neuroprotective effects of paeoniflorin on Alzheimer's disease
por: Zhang, Mengyuan, et al.
Publicado: (2023)

The Detrimental Action of Adenosine on Glutamate-Induced Cytotoxicity in PC12 Cells Can Be Shifted towards a Neuroprotective Role through A(1)AR Positive Allosteric Modulation
por: Vincenzi, Fabrizio, et al.
Publicado: (2020)

ERKs and mitochondria-related pathways are essential for glycyrrhizic acid-mediated neuroprotection against glutamate-induced toxicity in differentiated PC12 cells
por: Wang, D., et al.
Publicado: (2014)

Neuroprotection by Paeoniflorin against Nuclear Factor Kappa B-Induced Neuroinflammation on Spinal Cord Injury
por: Wang, Bin, et al.
Publicado: (2018)

Ginger and Propolis Exert Neuroprotective Effects against Monosodium Glutamate-Induced Neurotoxicity in Rats
por: Hussein, Usama K., et al.
Publicado: (2017)

An In Vitro Verification of the Effects of Paeoniflorin on Lipopolysaccharide-Exposed Microglia
por: Chen, Qiliang, et al.
Publicado: (2020)

Housefly Pupae-Derived Antioxidant Peptides Exerting Neuroprotective Effects on Hydrogen Peroxide-Induced Oxidative Damage in PC12 Cells
por: Sun, Tingting, et al.
Publicado: (2019)

Paeoniflorin exerts a nephroprotective effect on concanavalin A-induced damage through inhibition of macrophage infiltration
por: Liu, Cheng, et al.
Publicado: (2015)

Neuroprotective Effects of Four Phenylethanoid Glycosides on H(2)O(2)-Induced Apoptosis on PC12 Cells via the Nrf2/ARE Pathway
por: Li, Maiquan, et al.
Publicado: (2018)

Berberine protects against glutamate-induced oxidative stress and apoptosis in PC12 and N2a cells
por: Sadeghnia, Hamid Reza, et al.
Publicado: (2017)

Protective Effects of Marine Alkaloid Neolamellarin A Derivatives against Glutamate Induced PC12 Cell Apoptosis
por: Zhang, Kai, et al.
Publicado: (2022)

Upregulation of Glutaminyl Cyclase Contributes to ERS-Induced Apoptosis in PC12 Cells
por: Shang, Qi, et al.
Publicado: (2022)

Neuroprotective Effect of Abelmoschus manihot Flower Extracts against the H(2)O(2)-Induced Cytotoxicity, Oxidative Stress and Inflammation in PC12 Cells
por: Wang, Shih-Wei, et al.
Publicado: (2022)

Neuroprotective Effects of Exogenous Activin A on Oxygen-Glucose Deprivation in PC12 Cells
por: He, Jin-Ting, et al.
Publicado: (2011)

Paeoniflorin exerts neuroprotective effects by modulating the M1/M2 subset polarization of microglia/macrophages in the hippocampal CA1 region of vascular dementia rats via cannabinoid receptor 2
por: Luo, Xian-Qin, et al.
Publicado: (2018)

Rapid determination of paeoniflorin
por: Wiwanitkit, Viroj
Publicado: (2010)

Dried Rehmannia root protects against glutamate-induced cytotoxity to PC12 cells through energy metabolism-related pathways
por: Liu, Yong, et al.
Publicado: (2017)

Neurotropin exerts neuroprotective effects after spinal cord injury by inhibiting apoptosis and modulating cytokines
por: Yao, Xue, et al.
Publicado: (2020)

The Neuroprotective Effects of Arecae Pericarpium against Glutamate-Induced HT22 Cell Cytotoxicity
por: Jeong, Yun Hee, et al.
Publicado: (2022)

Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain
por: Zhou, Danli, et al.
Publicado: (2019)

Serum containing Tongqiaohuoxue decoction suppresses glutamate-induced PC12 cell injury☆
por: Wang, Ning, et al.
Publicado: (2012)

Neuroprotection by Neurotropin through Crosstalk of Neurotrophic and Innate Immune Receptors in PC12 Cells
por: Fukuda, Yu, et al.
Publicado: (2020)

Effects of phenolic constituents of daylily flowers on corticosterone- and glutamate-treated PC12 cells
por: Tian, Huan, et al.
Publicado: (2017)

The cellular model for Alzheimer's disease research: PC12 cells
por: Xie, Danni, et al.
Publicado: (2023)

Neuroprotective effects of Activin A on endoplasmic reticulum stress-mediated apoptotic and autophagic PC12 cell death
por: Xue, Long-xing, et al.
Publicado: (2017)

The Impact of Paeoniflorin on α-Synuclein Degradation Pathway
por: Cai, Zenglin, et al.
Publicado: (2015)

Paeoniflorin protects PC12 cells from oxygen-glucose deprivation/reoxygenation-induced injury via activating JAK2/STAT3 signaling
por: Zhang, Zhuo, et al.
Publicado: (2021)

Low Doses of Camptothecin Induced Hormetic and Neuroprotective Effects in PC12 Cells
por: Zhang, Chao, et al.
Publicado: (2015)

Irisin Exerts Neuroprotective Effects on Cultured Neurons by Regulating Astrocytes
por: Wang, Kexin, et al.
Publicado: (2018)

Neuroprotective effects of olanzapine against rotenone-induced toxicity in PC12 cells
por: Xiong, Ya-jie, et al.
Publicado: (2020)

The Neuroprotective and Neurotrophic Effects of Tremella fuciformis in PC12h Cells
por: Park, Kum Ju, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_1nvuqupc480df1g8r3fsrm5gk6