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Inactivation of MSH3 by promoter methylation correlates with primary tumor stage in nasopharyngeal carcinoma

The aim of this study was to investigate the inactivation of the MutS homolog human 3 (MSH3) gene by promoter methylation in nasopharyngeal carcinoma (NPC). Methylation-specific PCR, semi-quantitative reverse transcription PCR and immunohistochemical analysis were used to detect methylation and the...

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Detalles Bibliográficos
Autores principales: Ni, Haifeng, Jiang, Bo, Zhou, Zhen, Yuan, Xiaoyang, Cao, Xiaolin, Huang, Guangwu, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547962/
https://www.ncbi.nlm.nih.gov/pubmed/28656302
http://dx.doi.org/10.3892/ijmm.2017.3044