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Glutathione peroxidase 3 is a protective factor against acetaminophen-induced hepatotoxicity in vivo and in vitro

Acetaminophen (APAP) is a widely available antipyretic and analgesic; however, overdose of the drug inflicts severe damage to the liver. It is well established that the hepatotoxicity of APAP is initiated by formation of a reactive metabolite, N-acetyl-p-benzoquinone imine (NAPQI), which can be deto...

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Detalles Bibliográficos
Autores principales:	Kanno, Syu-Ichi, Tomizawa, Ayako, Yomogida, Shin, Hara, Akiyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547967/ https://www.ncbi.nlm.nih.gov/pubmed/28677736 http://dx.doi.org/10.3892/ijmm.2017.3049

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