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Bisphosphonate inhibits the expression of cyclin A2 at the transcriptional level in normal human oral keratinocytes

Nitrogen-containing bisphosphonates (N-BPs) are the most widely used anti-resorptive agents in the treatment of bone-related diseases. N-BPs inhibit bone resorption by specifically targeting osteoclasts, bone-resorbing cells. However, soft tissue toxicity, such as oral or gastrointestinal (GI) ulcer...

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Detalles Bibliográficos
Autores principales: Lee, Rachel S., Sohn, Suhjin, Shin, Ki-Hyuk, Kang, Mo K., Park, No-Hee, Kim, Reuben H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548072/
https://www.ncbi.nlm.nih.gov/pubmed/28713904
http://dx.doi.org/10.3892/ijmm.2017.3066