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Biocompatibility Evaluation of Four Dentin Adhesives Used as Indirect Pulp Capping Materials

BACKGROUND: In many cases, the indirect pulp treatment (IPT) is an acceptable treatment for deciduous teeth with reversible pulp inflammation. Various medicaments have been used for IPT, ranging from calcium hydroxide and glass ionomers to dentin adhesives. OBJECTIVE: This in vitro trial aimed to me...

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Autores principales: Cortés, Olga, Alcaina, Antonia, Bernabé, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University of Zagreb School of Dental Medicine, and Croatian Dental Society - Croatian Medical Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548215/
https://www.ncbi.nlm.nih.gov/pubmed/28827848
http://dx.doi.org/10.15644/asc51/2/4
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author Cortés, Olga
Alcaina, Antonia
Bernabé, Antonia
author_facet Cortés, Olga
Alcaina, Antonia
Bernabé, Antonia
author_sort Cortés, Olga
collection PubMed
description BACKGROUND: In many cases, the indirect pulp treatment (IPT) is an acceptable treatment for deciduous teeth with reversible pulp inflammation. Various medicaments have been used for IPT, ranging from calcium hydroxide and glass ionomers to dentin adhesives. OBJECTIVE: This in vitro trial aimed to measure cytotoxicity in a cell culture, comparing the following four adhesives: Xeno® V (XE), Excite® F DSC (EX), Adhese® OneF (AD) and Prime & Bond NT (PB). MATERIALS AND METHODS: The adhesives were prepared according to the manufacturer’s instructions. After 24 hours of exposure, the cell viability was evaluated using a photometrical test (MTT test). Data were subjected to analysis of variance (ANOVA). RESULTS: Adhesives, the main component of which was 2-hydroxyethyl methacrylate (HEMA), were found to be less cytotoxic, while those that included the monomer urethane dimethacrylate (UDMA were the most cytotoxic) in their composition. The effects on cell viability assay varied between the adhesives assayed with statistically significant differences. CONCLUSIONS: The results may support the argument that Adhese® OneF is the least cytotoxic of the adhesives assayed, and may be considered as an adhesive agent for indirect pulp treatment. However, Prime and Bond NT showed a reduced biocompatibility under the same conditions.
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spelling pubmed-55482152017-08-21 Biocompatibility Evaluation of Four Dentin Adhesives Used as Indirect Pulp Capping Materials Cortés, Olga Alcaina, Antonia Bernabé, Antonia Acta Stomatol Croat Original Scientific Paper(s) BACKGROUND: In many cases, the indirect pulp treatment (IPT) is an acceptable treatment for deciduous teeth with reversible pulp inflammation. Various medicaments have been used for IPT, ranging from calcium hydroxide and glass ionomers to dentin adhesives. OBJECTIVE: This in vitro trial aimed to measure cytotoxicity in a cell culture, comparing the following four adhesives: Xeno® V (XE), Excite® F DSC (EX), Adhese® OneF (AD) and Prime & Bond NT (PB). MATERIALS AND METHODS: The adhesives were prepared according to the manufacturer’s instructions. After 24 hours of exposure, the cell viability was evaluated using a photometrical test (MTT test). Data were subjected to analysis of variance (ANOVA). RESULTS: Adhesives, the main component of which was 2-hydroxyethyl methacrylate (HEMA), were found to be less cytotoxic, while those that included the monomer urethane dimethacrylate (UDMA were the most cytotoxic) in their composition. The effects on cell viability assay varied between the adhesives assayed with statistically significant differences. CONCLUSIONS: The results may support the argument that Adhese® OneF is the least cytotoxic of the adhesives assayed, and may be considered as an adhesive agent for indirect pulp treatment. However, Prime and Bond NT showed a reduced biocompatibility under the same conditions. University of Zagreb School of Dental Medicine, and Croatian Dental Society - Croatian Medical Association 2017-06 /pmc/articles/PMC5548215/ /pubmed/28827848 http://dx.doi.org/10.15644/asc51/2/4 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License.
spellingShingle Original Scientific Paper(s)
Cortés, Olga
Alcaina, Antonia
Bernabé, Antonia
Biocompatibility Evaluation of Four Dentin Adhesives Used as Indirect Pulp Capping Materials
title Biocompatibility Evaluation of Four Dentin Adhesives Used as Indirect Pulp Capping Materials
title_full Biocompatibility Evaluation of Four Dentin Adhesives Used as Indirect Pulp Capping Materials
title_fullStr Biocompatibility Evaluation of Four Dentin Adhesives Used as Indirect Pulp Capping Materials
title_full_unstemmed Biocompatibility Evaluation of Four Dentin Adhesives Used as Indirect Pulp Capping Materials
title_short Biocompatibility Evaluation of Four Dentin Adhesives Used as Indirect Pulp Capping Materials
title_sort biocompatibility evaluation of four dentin adhesives used as indirect pulp capping materials
topic Original Scientific Paper(s)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548215/
https://www.ncbi.nlm.nih.gov/pubmed/28827848
http://dx.doi.org/10.15644/asc51/2/4
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