Estrogen receptor coregulator binding modulators (ERXs) effectively target estrogen receptor positive human breast cancers

The majority of human breast cancer is estrogen receptor alpha (ER) positive. While anti-estrogens/aromatase inhibitors are initially effective, resistance to these drugs commonly develops. Therapy-resistant tumors often retain ER signaling, via interaction with critical oncogenic coregulator protei...

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Detalles Bibliográficos
Autores principales: Raj, Ganesh V, Sareddy, Gangadhara Reddy, Ma, Shihong, Lee, Tae-Kyung, Viswanadhapalli, Suryavathi, Li, Rui, Liu, Xihui, Murakami, Shino, Chen, Chien-Cheng, Lee, Wan-Ru, Mann, Monica, Krishnan, Samaya Rajeshwari, Manandhar, Bikash, Gonugunta, Vijay K, Strand, Douglas, Tekmal, Rajeshwar Rao, Ahn, Jung-Mo, Vadlamudi, Ratna K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548489/
https://www.ncbi.nlm.nih.gov/pubmed/28786813
http://dx.doi.org/10.7554/eLife.26857

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