Gastric Hyperplastic Polyps Associated with Proton Pump Inhibitor Use in a Case without a History of Helicobacter pylori Infection

A 56-year-old man with gastroesophageal reflux disease (GERD) was referred to our hospital. Esophagogastroduodenoscopy (EGD) revealed no evidence of any polypoid lesions in the stomach, and the patient had no history of Helicobacter pylori infection. He received omeprazole (20 mg) once daily for the...

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Autores principales: Miyamoto, Shuichi, Kato, Mototsugu, Matsuda, Kana, Abiko, Satoshi, Tsuda, Momoko, Mizushima, Takeshi, Yamamoto, Keiko, Ono, Shoko, Kudo, Takahiko, Shimizu, Yuichi, Hatanaka, Kanako C., Tsunematsu, Izumi, Sakamoto, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548674/
https://www.ncbi.nlm.nih.gov/pubmed/28717077
http://dx.doi.org/10.2169/internalmedicine.56.8040
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author Miyamoto, Shuichi
Kato, Mototsugu
Matsuda, Kana
Abiko, Satoshi
Tsuda, Momoko
Mizushima, Takeshi
Yamamoto, Keiko
Ono, Shoko
Kudo, Takahiko
Shimizu, Yuichi
Hatanaka, Kanako C.
Tsunematsu, Izumi
Sakamoto, Naoya
author_facet Miyamoto, Shuichi
Kato, Mototsugu
Matsuda, Kana
Abiko, Satoshi
Tsuda, Momoko
Mizushima, Takeshi
Yamamoto, Keiko
Ono, Shoko
Kudo, Takahiko
Shimizu, Yuichi
Hatanaka, Kanako C.
Tsunematsu, Izumi
Sakamoto, Naoya
author_sort Miyamoto, Shuichi
collection PubMed
description A 56-year-old man with gastroesophageal reflux disease (GERD) was referred to our hospital. Esophagogastroduodenoscopy (EGD) revealed no evidence of any polypoid lesions in the stomach, and the patient had no history of Helicobacter pylori infection. He received omeprazole (20 mg) once daily for the GERD. EGD was performed at 1 year after the start of omeprazole administration, and this time, gastric hyperplastic polyps (GHPs) were detected. The GHPs increased in size as the omeprazole treatment continued, but they markedly decreased in size following omeprazole discontinuation. Thus, the administration of proton pump inhibitors may be a risk factor for the development of GHP independent of H. pylori infection.
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spelling pubmed-55486742017-08-11 Gastric Hyperplastic Polyps Associated with Proton Pump Inhibitor Use in a Case without a History of Helicobacter pylori Infection Miyamoto, Shuichi Kato, Mototsugu Matsuda, Kana Abiko, Satoshi Tsuda, Momoko Mizushima, Takeshi Yamamoto, Keiko Ono, Shoko Kudo, Takahiko Shimizu, Yuichi Hatanaka, Kanako C. Tsunematsu, Izumi Sakamoto, Naoya Intern Med Case Report A 56-year-old man with gastroesophageal reflux disease (GERD) was referred to our hospital. Esophagogastroduodenoscopy (EGD) revealed no evidence of any polypoid lesions in the stomach, and the patient had no history of Helicobacter pylori infection. He received omeprazole (20 mg) once daily for the GERD. EGD was performed at 1 year after the start of omeprazole administration, and this time, gastric hyperplastic polyps (GHPs) were detected. The GHPs increased in size as the omeprazole treatment continued, but they markedly decreased in size following omeprazole discontinuation. Thus, the administration of proton pump inhibitors may be a risk factor for the development of GHP independent of H. pylori infection. The Japanese Society of Internal Medicine 2017-07-15 /pmc/articles/PMC5548674/ /pubmed/28717077 http://dx.doi.org/10.2169/internalmedicine.56.8040 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Miyamoto, Shuichi
Kato, Mototsugu
Matsuda, Kana
Abiko, Satoshi
Tsuda, Momoko
Mizushima, Takeshi
Yamamoto, Keiko
Ono, Shoko
Kudo, Takahiko
Shimizu, Yuichi
Hatanaka, Kanako C.
Tsunematsu, Izumi
Sakamoto, Naoya
Gastric Hyperplastic Polyps Associated with Proton Pump Inhibitor Use in a Case without a History of Helicobacter pylori Infection
title Gastric Hyperplastic Polyps Associated with Proton Pump Inhibitor Use in a Case without a History of Helicobacter pylori Infection
title_full Gastric Hyperplastic Polyps Associated with Proton Pump Inhibitor Use in a Case without a History of Helicobacter pylori Infection
title_fullStr Gastric Hyperplastic Polyps Associated with Proton Pump Inhibitor Use in a Case without a History of Helicobacter pylori Infection
title_full_unstemmed Gastric Hyperplastic Polyps Associated with Proton Pump Inhibitor Use in a Case without a History of Helicobacter pylori Infection
title_short Gastric Hyperplastic Polyps Associated with Proton Pump Inhibitor Use in a Case without a History of Helicobacter pylori Infection
title_sort gastric hyperplastic polyps associated with proton pump inhibitor use in a case without a history of helicobacter pylori infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548674/
https://www.ncbi.nlm.nih.gov/pubmed/28717077
http://dx.doi.org/10.2169/internalmedicine.56.8040
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