Thrombolysis-related Multiple Lobar Hemorrhaging in Cerebral Amyloid Angiopathy with Extensive Strictly Lobar Cerebral Microbleeding

A hemi-paralyzed 86-year-old man was diagnosed with ischemic stroke and underwent thrombolysis. Pre-thrombolysis brain magnetic resonance imaging revealed extensive strictly lobar cerebral microbleeding (CMB). Post-thrombolytic computed tomography revealed asymptomatic multiple intracerebral hemorrh...

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Autores principales: Eriguchi, Makoto, Yakushiji, Yusuke, Tanaka, Jun, Nishihara, Masashi, Hara, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548688/
https://www.ncbi.nlm.nih.gov/pubmed/28717091
http://dx.doi.org/10.2169/internalmedicine.56.8007
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author Eriguchi, Makoto
Yakushiji, Yusuke
Tanaka, Jun
Nishihara, Masashi
Hara, Hideo
author_facet Eriguchi, Makoto
Yakushiji, Yusuke
Tanaka, Jun
Nishihara, Masashi
Hara, Hideo
author_sort Eriguchi, Makoto
collection PubMed
description A hemi-paralyzed 86-year-old man was diagnosed with ischemic stroke and underwent thrombolysis. Pre-thrombolysis brain magnetic resonance imaging revealed extensive strictly lobar cerebral microbleeding (CMB). Post-thrombolytic computed tomography revealed asymptomatic multiple intracerebral hemorrhaging (ICH). His age, CMB topography, and decreased cerebral spinal fluid amyloid-β 40 and 42 levels were compatible with a diagnosis of cerebral amyloid angiopathy (CAA). There is no consensus on the safety of thrombolysis for acute stroke patients with CAA. Patients with CAA might have a higher incidence of thrombolysis-related ICH than those without CAA.
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spelling pubmed-55486882017-08-11 Thrombolysis-related Multiple Lobar Hemorrhaging in Cerebral Amyloid Angiopathy with Extensive Strictly Lobar Cerebral Microbleeding Eriguchi, Makoto Yakushiji, Yusuke Tanaka, Jun Nishihara, Masashi Hara, Hideo Intern Med Case Report A hemi-paralyzed 86-year-old man was diagnosed with ischemic stroke and underwent thrombolysis. Pre-thrombolysis brain magnetic resonance imaging revealed extensive strictly lobar cerebral microbleeding (CMB). Post-thrombolytic computed tomography revealed asymptomatic multiple intracerebral hemorrhaging (ICH). His age, CMB topography, and decreased cerebral spinal fluid amyloid-β 40 and 42 levels were compatible with a diagnosis of cerebral amyloid angiopathy (CAA). There is no consensus on the safety of thrombolysis for acute stroke patients with CAA. Patients with CAA might have a higher incidence of thrombolysis-related ICH than those without CAA. The Japanese Society of Internal Medicine 2017-07-15 /pmc/articles/PMC5548688/ /pubmed/28717091 http://dx.doi.org/10.2169/internalmedicine.56.8007 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Eriguchi, Makoto
Yakushiji, Yusuke
Tanaka, Jun
Nishihara, Masashi
Hara, Hideo
Thrombolysis-related Multiple Lobar Hemorrhaging in Cerebral Amyloid Angiopathy with Extensive Strictly Lobar Cerebral Microbleeding
title Thrombolysis-related Multiple Lobar Hemorrhaging in Cerebral Amyloid Angiopathy with Extensive Strictly Lobar Cerebral Microbleeding
title_full Thrombolysis-related Multiple Lobar Hemorrhaging in Cerebral Amyloid Angiopathy with Extensive Strictly Lobar Cerebral Microbleeding
title_fullStr Thrombolysis-related Multiple Lobar Hemorrhaging in Cerebral Amyloid Angiopathy with Extensive Strictly Lobar Cerebral Microbleeding
title_full_unstemmed Thrombolysis-related Multiple Lobar Hemorrhaging in Cerebral Amyloid Angiopathy with Extensive Strictly Lobar Cerebral Microbleeding
title_short Thrombolysis-related Multiple Lobar Hemorrhaging in Cerebral Amyloid Angiopathy with Extensive Strictly Lobar Cerebral Microbleeding
title_sort thrombolysis-related multiple lobar hemorrhaging in cerebral amyloid angiopathy with extensive strictly lobar cerebral microbleeding
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548688/
https://www.ncbi.nlm.nih.gov/pubmed/28717091
http://dx.doi.org/10.2169/internalmedicine.56.8007
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