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Polyphyllin I suppresses human osteosarcoma growth by inactivation of Wnt/β-catenin pathway in vitro and in vivo
Osteosarcoma is the most common primary bone cancer in children and adolescents. In spite of aggressive treatment, osteosarcoma has a high mortality rate with minimal improvements in survival over past few decades. Polyphyllin I (PPI), a component in the traditional Chinese medicinal herb Paris poly...
Autores principales: | Chang, Junli, Li, Yimian, Wang, Xianyang, Hu, Shaopu, Wang, Hongshen, Shi, Qi, Wang, Yongjun, Yang, Yanping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548759/ https://www.ncbi.nlm.nih.gov/pubmed/28790389 http://dx.doi.org/10.1038/s41598-017-07194-9 |
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