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Hypoxia impairs agonist-induced integrin α(IIb)β(3) activation and platelet aggregation

Under ischemic conditions, tissues are exposed to hypoxia. Although human physiology, to a certain extent, can adapt to hypoxic conditions, the impact of low oxygen levels on platelet function is unresolved. Therefore, we explored how reduction of atmospheric oxygen levels to 1% might affect agonist...

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Detalles Bibliográficos
Autores principales:	Kiouptsi, Klytaimnistra, Gambaryan, Stepan, Walter, Elena, Walter, Ulrich, Jurk, Kerstin, Reinhardt, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548784/ https://www.ncbi.nlm.nih.gov/pubmed/28790378 http://dx.doi.org/10.1038/s41598-017-07988-x

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