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Safety of flexible endoscopic biopsy of the pharynx and larynx under topical anesthesia
Recent advancements in transnasal endoscopy enable a shift in diagnostic workup of lesions in the pharynx and larynx, from an examination with biopsy under general anesthesia to an office-based examination with flexible endoscopic biopsy under topical anesthesia. Procedural complications were evalua...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548855/ https://www.ncbi.nlm.nih.gov/pubmed/28639059 http://dx.doi.org/10.1007/s00405-017-4647-z |
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author | Wellenstein, David J. de Witt, Joey K. Schutte, Henrieke W. Honings, Jimmie van den Hoogen, Frank J. A. Marres, Henri A. M. Takes, Robert P. van den Broek, Guido B. |
author_facet | Wellenstein, David J. de Witt, Joey K. Schutte, Henrieke W. Honings, Jimmie van den Hoogen, Frank J. A. Marres, Henri A. M. Takes, Robert P. van den Broek, Guido B. |
author_sort | Wellenstein, David J. |
collection | PubMed |
description | Recent advancements in transnasal endoscopy enable a shift in diagnostic workup of lesions in the pharynx and larynx, from an examination with biopsy under general anesthesia to an office-based examination with flexible endoscopic biopsy under topical anesthesia. Procedural complications were evaluated to assess the safety of office-based flexible endoscopic biopsy in patients with benign and malignant laryngopharyngeal lesions. Patients who underwent flexible endoscopic biopsy from 2012 to 2016 were evaluated retrospectively. Complications were classified using the Clavien–Dindo classification of surgical complications. A total of 201 flexible endoscopic biopsies were performed in 187 patients. Two Clavien–Dindo grade I (laryngospasm and anterior epistaxis), one grade II (laryngeal bleeding), and one grade IIIb (laryngeal edema) complication were observed. The first complication was self-limiting and the other three required an intervention. All patients fully recovered without sequelae. Flexible endoscopic biopsy appears to be a safe office-based procedure for the diagnosis of benign and malignant laryngopharyngeal lesions. |
format | Online Article Text |
id | pubmed-5548855 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-55488552017-08-24 Safety of flexible endoscopic biopsy of the pharynx and larynx under topical anesthesia Wellenstein, David J. de Witt, Joey K. Schutte, Henrieke W. Honings, Jimmie van den Hoogen, Frank J. A. Marres, Henri A. M. Takes, Robert P. van den Broek, Guido B. Eur Arch Otorhinolaryngol Head and Neck Recent advancements in transnasal endoscopy enable a shift in diagnostic workup of lesions in the pharynx and larynx, from an examination with biopsy under general anesthesia to an office-based examination with flexible endoscopic biopsy under topical anesthesia. Procedural complications were evaluated to assess the safety of office-based flexible endoscopic biopsy in patients with benign and malignant laryngopharyngeal lesions. Patients who underwent flexible endoscopic biopsy from 2012 to 2016 were evaluated retrospectively. Complications were classified using the Clavien–Dindo classification of surgical complications. A total of 201 flexible endoscopic biopsies were performed in 187 patients. Two Clavien–Dindo grade I (laryngospasm and anterior epistaxis), one grade II (laryngeal bleeding), and one grade IIIb (laryngeal edema) complication were observed. The first complication was self-limiting and the other three required an intervention. All patients fully recovered without sequelae. Flexible endoscopic biopsy appears to be a safe office-based procedure for the diagnosis of benign and malignant laryngopharyngeal lesions. Springer Berlin Heidelberg 2017-06-21 2017 /pmc/articles/PMC5548855/ /pubmed/28639059 http://dx.doi.org/10.1007/s00405-017-4647-z Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Head and Neck Wellenstein, David J. de Witt, Joey K. Schutte, Henrieke W. Honings, Jimmie van den Hoogen, Frank J. A. Marres, Henri A. M. Takes, Robert P. van den Broek, Guido B. Safety of flexible endoscopic biopsy of the pharynx and larynx under topical anesthesia |
title | Safety of flexible endoscopic biopsy of the pharynx and larynx under topical anesthesia |
title_full | Safety of flexible endoscopic biopsy of the pharynx and larynx under topical anesthesia |
title_fullStr | Safety of flexible endoscopic biopsy of the pharynx and larynx under topical anesthesia |
title_full_unstemmed | Safety of flexible endoscopic biopsy of the pharynx and larynx under topical anesthesia |
title_short | Safety of flexible endoscopic biopsy of the pharynx and larynx under topical anesthesia |
title_sort | safety of flexible endoscopic biopsy of the pharynx and larynx under topical anesthesia |
topic | Head and Neck |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548855/ https://www.ncbi.nlm.nih.gov/pubmed/28639059 http://dx.doi.org/10.1007/s00405-017-4647-z |
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