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Deficiency of COX7RP, a mitochondrial supercomplex assembly promoting factor, lowers blood glucose level in mice

Mitochondria are essential organelles to efficiently produce ATP by ATP-synthase, which uses a proton-gradient generated by respiratory chain complexes. We previously demonstrated that COX7RP/COX7A2L/SCAF1 is a key molecule that promotes respiratory supercomplex assembly and regulates energy generat...

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Detalles Bibliográficos
Autores principales: Shiba, Sachiko, Ikeda, Kazuhiro, Horie-Inoue, Kuniko, Nakayama, Akitoshi, Tanaka, Tomoaki, Inoue, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548899/
https://www.ncbi.nlm.nih.gov/pubmed/28790391
http://dx.doi.org/10.1038/s41598-017-08081-z