Single-cell analyses identify bioengineered niches for enhanced maintenance of hematopoietic stem cells

The in vitro expansion of long-term hematopoietic stem cells (HSCs) remains a substantial challenge, largely because of our limited understanding of the mechanisms that control HSC fate choices. Using single-cell multigene expression analysis and time-lapse microscopy, here we define gene expression...

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Detalles Bibliográficos
Autores principales: Roch, Aline, Giger, Sonja, Girotra, Mukul, Campos, Vasco, Vannini, Nicola, Naveiras, Olaia, Gobaa, Samy, Lutolf, Matthias P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548907/
https://www.ncbi.nlm.nih.gov/pubmed/28790449
http://dx.doi.org/10.1038/s41467-017-00291-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548907/
https://www.ncbi.nlm.nih.gov/pubmed/28790449
http://dx.doi.org/10.1038/s41467-017-00291-3

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