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Performance of objective functions and optimisation procedures for parameter estimation in system biology models
Mathematical modelling of signalling pathways aids experimental investigation in system and synthetic biology. Ever increasing data availability prompts the development of large dynamic models with numerous parameters. In this paper, we investigate how the number of unknown parameters affects the co...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548920/ https://www.ncbi.nlm.nih.gov/pubmed/28804640 http://dx.doi.org/10.1038/s41540-017-0023-2 |