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Performance of objective functions and optimisation procedures for parameter estimation in system biology models

Mathematical modelling of signalling pathways aids experimental investigation in system and synthetic biology. Ever increasing data availability prompts the development of large dynamic models with numerous parameters. In this paper, we investigate how the number of unknown parameters affects the co...

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Detalles Bibliográficos
Autores principales:	Degasperi, Andrea, Fey, Dirk, Kholodenko, Boris N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548920/ https://www.ncbi.nlm.nih.gov/pubmed/28804640 http://dx.doi.org/10.1038/s41540-017-0023-2

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