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Genome-wide Single-Molecule Footprinting Reveals High RNA Polymerase II Turnover at Paused Promoters

Transcription initiation entails chromatin opening followed by pre-initiation complex formation and RNA polymerase II recruitment. Subsequent polymerase elongation requires additional signals, resulting in increased residence time downstream of the start site, a phenomenon referred to as pausing. He...

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Detalles Bibliográficos
Autores principales:	Krebs, Arnaud R., Imanci, Dilek, Hoerner, Leslie, Gaidatzis, Dimos, Burger, Lukas, Schübeler, Dirk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548954/ https://www.ncbi.nlm.nih.gov/pubmed/28735898 http://dx.doi.org/10.1016/j.molcel.2017.06.027

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