Safety, immunogenicity, and cross-species protection of a plasmid DNA encoding Plasmodium falciparum SERA5 polypeptide, microbial epitopes and chemokine genes in mice and olive baboons

Incorporation of biomolecular epitopes to malarial antigens should be explored in the development of strain-transcending malarial vaccines. The present study sought to determine safety, immunogenicity and cross-species efficacy ofPlasmodium falciparum serine repeat antigen 5 polypeptide co-expressed...

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Detalles Bibliográficos
Autores principales: Onkoba, Nyamongo, Mumo, Ruth M., Ochanda, Horace, Omwandho, Charles, Ozwara, Hastings S., Egwang, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548993/
https://www.ncbi.nlm.nih.gov/pubmed/28808204
http://dx.doi.org/10.7555/JBR.31.20160025

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