Cargando…

Mangiferin induces apoptosis in human ovarian adenocarcinoma OVCAR3 cells via the regulation of Notch3

Ovarian cancer is the most lethal gynecological malignancy in the world. Our previous studies showed that mangiferin, purified from plant source, possessed anti-neoplasm effect on human lung adenocarcinoma A549 cells. This study aimed to determine the apoptosis-inducing effect of mangiferin on human...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zou, Bingyu, Wang, Hailian, Liu, Yilong, Qi, Ping, Lei, Tiantian, Sun, Minghan, Wang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549032/ https://www.ncbi.nlm.nih.gov/pubmed/28714011 http://dx.doi.org/10.3892/or.2017.5814

Ejemplares similares

Anti-neoplastic effect of mangiferin on human ovarian adenocarcinoma OVCAR8 cells via the regulation of YAP
por: He, Wenjing, et al.
Publicado: (2019)

Mangiferin induces islet regeneration in aged mice through regulating p16(INK4a)
por: Wang, Hailian, et al.
Publicado: (2018)

Galectin-9 induces apoptosis in OVCAR-3 ovarian cancer cell through mitochondrial pathway
por: Jafari, Seyyed Mehdi, et al.
Publicado: (2018)

MicroRNA-1284 Inhibits Cell Viability and Induces Apoptosis of Ovarian Cancer Cell Line OVCAR3
por: Pan, Changqing, et al.
Publicado: (2016)

Theaflavin-3, 3′-digallate decreases human ovarian carcinoma OVCAR-3 cell-induced angiogenesis via Akt and Notch-1 pathways, not via MAPK pathways
por: GAO, YING, et al.
Publicado: (2015)

Antitumor Effects of Turmeric on OVCAR-3 Ovarian Cancer Cell Lines
por: Gurer, Hulusi Goktug, et al.
Publicado: (2022)

Leptin stimulation of cell cycle and inhibition of apoptosis gene and protein expression in OVCAR-3 ovarian cancer cells
por: Ptak, Anna, et al.
Publicado: (2012)

Transcriptome profile of OVCAR3 cisplatin-resistant ovarian cancer cell line
por: Sakhare, Shruti S, et al.
Publicado: (2014)

17β-Estradiol Stimulates Generation of Reactive Species Oxygen and Nitric Oxide in Ovarian Adenocarcinoma Cells (OVCAR 3)
por: Maleki, Jafar, et al.
Publicado: (2015)

Synergistic Effect of COX-2 Inhibitor on Paclitaxel-Induced Apoptosis in the Human Ovarian Cancer Cell Line OVCAR-3
por: Kim, Hee Jung, et al.
Publicado: (2014)

miR-940 Upregulation Suppresses Cell Proliferation and Induces Apoptosis by Targeting PKC-δ in Ovarian Cancer OVCAR3 Cells
por: Wang, Fang, et al.
Publicado: (2017)

Molecular mechanisms underlying mangiferin-induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells
por: SHI, WEI, et al.
Publicado: (2016)

Synergistic Effect of Saccharin and Caffeine on Antiproliferative Activity in Human Ovarian Carcinoma Ovcar-3 Cells
por: Lee, Sun Ju, et al.
Publicado: (2023)

OVCAR-3 Spheroid-Derived Cells Display Distinct Metabolic Profiles
por: Vermeersch, Kathleen A., et al.
Publicado: (2015)

Thyrostimulin-TSHR signaling promotes the proliferation of NIH:OVCAR-3 ovarian cancer cells via trans-regulation of the EGFR pathway
por: Huang, Wei-Lin, et al.
Publicado: (2016)

Overexpression of miR-148a inhibits viability and invasion of ovarian cancer OVCAR3 cells by targeting FOXO3
por: Zhu, Dandan, et al.
Publicado: (2019)

Molecular expression of adenosine receptors in OVCAR-3, Caov-4 and SKOV-3 human ovarian cancer cell lines
por: Hajiahmadi, S., et al.
Publicado: (2015)

RNA interference-mediated FANCF silencing sensitizes OVCAR3 ovarian cancer cells to adriamycin through increased adriamycin-induced apoptosis dependent on JNK activation
por: HE, MIAO, et al.
Publicado: (2013)

RNA interference-mediated FANCF silencing sensitizes OVCAR3 ovarian cancer cells to adriamycin through increased adriamycin-induced apoptosis dependent on JNK activation
por: He, Miao, et al.
Publicado: (2022)

Catalpol Suppresses Proliferation and Facilitates Apoptosis of OVCAR-3 Ovarian Cancer Cells through Upregulating MicroRNA-200 and Downregulating MMP-2 Expression
por: Gao, Na, et al.
Publicado: (2014)

Expression of Dual-Specificity Phosphatase 2 (DUSP2) in Patients with Serous Ovarian Carcinoma and in SKOV3 and OVCAR3 Cells In Vitro
por: Liu, Wei, et al.
Publicado: (2019)

Effects of metastasis-associated in colon cancer 1 inhibition by small hairpin RNA on ovarian carcinoma OVCAR-3 cells
por: Zhang, Ruitao, et al.
Publicado: (2011)

Cytokines secreted by human Wharton's jelly stem cells inhibit the proliferation of ovarian cancer (OVCAR3) cells in vitro
por: Kalamegam, Gauthaman, et al.
Publicado: (2019)

Anti-proliferative and anti-apoptotic effects of grape seed extract on chemo-resistant OVCAR-3 ovarian cancer cells
por: Homayoun, Mansour, et al.
Publicado: (2020)

The miR‐200 family differentially regulates sensitivity to paclitaxel and carboplatin in human ovarian carcinoma OVCAR‐3 and MES‐OV cells
por: Brozovic, Anamaria, et al.
Publicado: (2015)

Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis
por: Kalamegam, Gauthaman, et al.
Publicado: (2018)

Kaempferol Sensitizes Human Ovarian Cancer Cells-OVCAR-3 and SKOV-3 to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis via JNK/ERK-CHOP Pathway and Up-Regulation of Death Receptors 4 and 5
por: Zhao, Yingmei, et al.
Publicado: (2017)

Inhibition of Proliferation, Migration, and Invasion by Knockdown of Pyruvate Kinase-M2 (PKM2) in Ovarian Cancer SKOV3 and OVCAR3 Cells
por: Miao, Yi, et al.
Publicado: (2016)

MicroRNA profiling of a CD133(+) spheroid-forming subpopulation of the OVCAR3 human ovarian cancer cell line
por: Nam, Eun Ji, et al.
Publicado: (2012)

Corrigendum: Human Wharton’s Jelly stem cell (hWJSC) extracts inhibit ovarian cancer cell lines OVCAR3 and SKOV3 in vitro by inducing cell cycle arrest and apoptosis
por: Kalamegam, Gauthaman, et al.
Publicado: (2023)

Theaflavin-3,3′-Digallate Suppresses Human Ovarian Carcinoma OVCAR-3 Cells by Regulating the Checkpoint Kinase 2 and p27 kip1 Pathways
por: Gao, Ying, et al.
Publicado: (2019)

Changes in the transcriptional profile in response to overexpression of the osteopontin-c splice isoform in ovarian (OvCar-3) and prostate (PC-3) cancer cell lines
por: Tilli, Tatiana M, et al.
Publicado: (2014)

All-trans retinoic acid and genistein induce cell apoptosis in OVCAR-3 cells by increasing the P14 tumor suppressor gene
por: Dastjerdi, Mehdi Nikbakht, et al.
Publicado: (2016)

Resveratrol, Acetyl-Resveratrol, and Polydatin Exhibit Antigrowth Activity against 3D Cell Aggregates of the SKOV-3 and OVCAR-8 Ovarian Cancer Cell Lines
por: Hogg, Simon J., et al.
Publicado: (2015)

Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma
por: Yang, Yong, et al.
Publicado: (2018)

Effect of Mangiferin and Mahanimbine on Glucose Utilization in 3T3-L1 cells
por: Kumar, B Dinesh, et al.
Publicado: (2013)

Discovery of a Novel Benzenesulfonamide Analogue That Inhibits Proliferation and Metastasis Against Ovarian Cancer OVCAR-8 Cells
por: Jia, Yanyan, et al.
Publicado: (2020)

Orostachys japonicus induce p53‐dependent cell cycle arrest through the MAPK signaling pathway in OVCAR‐3 human ovarian cancer cells
por: Lee, Kyung‐Sun, et al.
Publicado: (2018)

Characterisation of Ovarian Cancer Cell Line NIH-OVCAR3 and Implications of Genomic, Transcriptomic, Proteomic and Functional DNA Damage Response Biomarkers for Therapeutic Targeting
por: Bradbury, Alice, et al.
Publicado: (2020)

Inward Outward Signaling in Ovarian Cancer: Morpho-Phospho-Proteomic Profiling Upon Application of Hypoxia and Shear Stress Characterizes the Adaptive Plasticity of OVCAR-3 and SKOV-3 Cells
por: Bileck, Andrea, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_450np84cn3fqis22vmlts0iuip