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Glioblastoma entities express subtle differences in molecular composition and response to treatment
Glioblastoma (GBM) is a grade IV astrocytoma. GBM patients show resistance to chemotherapy such as temozolomide (TMZ), the gold standard treatment. In order to simulate the molecular mechanisms behind the different chemotherapeutic responses in GBM patients we compared the cellular heterogeneity and...
Autores principales: | Balça-Silva, Joana, Matias, Diana, Do Carmo, Anália, Dubois, Luiz Gustavo, Gonçalves, Ana Cristina, Girão, Henrique, Silva Canedo, Nathalie Henriques, Correia, Ana Helena, De Souza, Jorge Marcondes, Sarmento-Ribeiro, Ana Bela, Lopes, Maria Celeste, Moura-Neto, Vivaldo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549060/ https://www.ncbi.nlm.nih.gov/pubmed/28714013 http://dx.doi.org/10.3892/or.2017.5799 |
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