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Role of AmpR in the High Expression of the Plasmid-Encoded AmpC β-Lactamase CFE-1
CFE-1 is a unique plasmid-encoded AmpC β-lactamase with the regulator gene ampR. It imparts high resistance to most cephalosporins with constitutive high-level β-lactamase activity. Here, the β-lactamase activities and expression levels of ampC with or without ampR were investigated. Results suggest...
Autores principales: | Nakano, Ryuichi, Nakano, Akiyo, Yano, Hisakazu, Okamoto, Ryoichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549177/ https://www.ncbi.nlm.nih.gov/pubmed/28808689 http://dx.doi.org/10.1128/mSphere.00192-17 |
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