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Assessment of pharmacogenetic tests: presenting measures of clinical validity and potential population impact in association studies

The progressing discovery of genetic variants associated with drug-related adverse events has raised expectations for pharmacogenetic tests to improve drug efficacy and safety. To further the use of pharmacogenetics in health care, tests with sufficient potential to improve efficacy and safety, as r...

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Detalles Bibliográficos
Autores principales: Tonk, E C M, Gurwitz, D, Maitland-van der Zee, A-H, Janssens, A C J W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549182/
https://www.ncbi.nlm.nih.gov/pubmed/27168098
http://dx.doi.org/10.1038/tpj.2016.34