Cargando…

IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis

BACKGROUND: Methotrexate (MTX) is the standard first-line therapy in rheumatoid arthritis (RA) with variable clinical efficacy that is difficult to predict. The glycosylation status of immunoglobulin G (IgG) is altered in RA and influenced by MTX treatment. We aimed to further investigate if IgG gly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lundström, Susanna L., Hensvold, Aase H., Rutishauser, Dorothea, Klareskog, Lars, Ytterberg, A. Jimmy, Zubarev, Roman A., Catrina, Anca I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549282/ https://www.ncbi.nlm.nih.gov/pubmed/28793911 http://dx.doi.org/10.1186/s13075-017-1389-7

Ejemplares similares

IgG Antibodies to Cyclic Citrullinated Peptides Exhibit Profiles Specific in Terms of IgG Subclasses, Fc-Glycans and a Fab-Peptide Sequence
por: Lundström, Susanna L., et al.
Publicado: (2014)

Altered Fc galactosylation in IgG(4) is a potential serum marker for chronic lung disease
por: Heyder, Tina, et al.
Publicado: (2018)

IgG1 Fc N-glycan galactosylation as a biomarker for immune activation
por: de Jong, Sanne E., et al.
Publicado: (2016)

Molecular signature of methotrexate response among rheumatoid arthritis patients
por: Brynedal, Boel, et al.
Publicado: (2023)

Is IgG galactosylation the relevant factor for pregnancy-induced remission of rheumatoid arthritis?
por: Förger, Frauke, et al.
Publicado: (2010)

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets
por: van Osch, Thijs L.J., et al.
Publicado: (2022)

A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis
por: Grönwall, Caroline, et al.
Publicado: (2021)

Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis
por: Shchetynsky, Klementy, et al.
Publicado: (2017)

Serum RANKL levels associate with anti- citrullinated protein antibodies in early untreated rheumatoid arthritis and are modulated following methotrexate
por: Hensvold, Aase Haj, et al.
Publicado: (2015)

Patients with anti-Jo1 antibodies display a characteristic IgG Fc-glycan profile which is further enhanced in anti-Jo1 autoantibodies
por: Fernandes-Cerqueira, Cátia, et al.
Publicado: (2018)

Age-related galactosylation of the N-linked oligosaccharides of human serum IgG
Publicado: (1988)

Alteration of Serum IgG Galactosylation as a Potential Biomarker for Diagnosis of Neuroblastoma
por: Qin, Wenjun, et al.
Publicado: (2018)

Variability of serum IgG sialylation and galactosylation degree in women with advanced endometriosis
por: Sołkiewicz, Katarzyna, et al.
Publicado: (2021)

SpotLight Proteomics: uncovering the hidden blood proteome improves diagnostic power of proteomics
por: Lundström, Susanna L., et al.
Publicado: (2017)

SpotLight Proteomics—A IgG-Enrichment Phenotype Profiling Approach with Clinical Implications
por: Lundström, Susanna L., et al.
Publicado: (2019)

A unique natural human IgG antibody with anti-alpha-galactosyl specificity
Publicado: (1984)

The Role of IgG Fc Region N-Glycosylation in the Pathomechanism of Rheumatoid Arthritis
por: Gyebrovszki, Balázs, et al.
Publicado: (2022)

Tocilizumab decreases T cells but not macrophages in the synovium of patients with rheumatoid arthritis while it increases the levels of serum interleukin-6 and RANKL
por: Chatzidionysiou, Katerina, et al.
Publicado: (2021)

Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types
por: Ren, Shifang, et al.
Publicado: (2016)

A novel glycosidase plate-based assay for the quantification of galactosylation and sialylation on human IgG
por: Rebello, Osmond D., et al.
Publicado: (2020)

Distinct Fluorescence Optical Imaging Patient Clusters Emerge for Seropositive and Seronegative Rheumatoid Arthritis
por: Kisten, Yogan, et al.
Publicado: (2023)

Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss
por: Krishnamurthy, Akilan, et al.
Publicado: (2016)

Enhanced Immunomodulatory Effect of Intravenous Immunoglobulin by Fc Galactosylation and Nonfucosylation
por: Mimura, Yusuke, et al.
Publicado: (2022)

Diagnostic Significance of Serum IgG Galactosylation in CA19-9-Negative Pancreatic Carcinoma Patients
por: Zhong, Ailing, et al.
Publicado: (2019)

Galactosylation and Sialylation Levels of IgG Predict Relapse in Patients With PR3-ANCA Associated Vasculitis
por: Kemna, Michael J., et al.
Publicado: (2017)

mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses compared to an adenovirus-based vaccine
por: Buhre, Jana Sophia, et al.
Publicado: (2023)

Citrullination facilitates cross-reactivity of rheumatoid factor with non-IgG1 Fc epitopes in rheumatoid arthritis
por: Trela, Malgorzata, et al.
Publicado: (2019)

Erratum: Enhanced Immunomodulatory Effect of Intravenous Immunoglobulin by Fc Galactosylation and Nonfucosylation
Publicado: (2022)

Prospective Studies on the Risk of Rheumatoid Arthritis: The European Risk RA Registry
por: Studenic, Paul, et al.
Publicado: (2022)

Specificity of fc receptors for IgG2a, IgG1/IgG2b, and IgE on rat macrophages
Publicado: (1981)

B-lymphocytes activation by the Fc region of IgG
Publicado: (1977)

Fc-Mediated Functions of Porcine IgG Subclasses
por: Paudyal, Basudev, et al.
Publicado: (2022)

Abnormal N‐glycan fucosylation, galactosylation, and sialylation of IgG in adults with classical galactosemia, influence of dietary galactose intake
por: Treacy, Eileen P., et al.
Publicado: (2021)

Human IgG/FcγR Interactions Are Modulated by Streptococcal IgG Glycan Hydrolysis
por: Allhorn, Maria, et al.
Publicado: (2008)

The role of Fc–FcγR interactions in IgG-mediated microbial neutralization
por: Bournazos, Stylianos, et al.
Publicado: (2015)

IgG4 antibodies from patients with asymptomatic bancroftian filariasis inhibit the binding of IgG1 and IgG2 to C1q in a Fc-Fc-dependent mechanism
por: Prodjinotho, Ulrich F., et al.
Publicado: (2019)

On the Use of Surface Plasmon Resonance Biosensing to Understand IgG-FcγR Interactions
por: Forest-Nault, Catherine, et al.
Publicado: (2021)

Posttranslational Targeting of a Recombinant Protein Promotes Its Efficient Secretion into the Escherichia coli Periplasm
por: Ytterberg, A. Jimmy, et al.
Publicado: (2019)

Human natural anti-alpha-galactosyl IgG. II. The specific recognition of alpha (1----3)-linked galactose residues
Publicado: (1985)

IgG Galactosylation status combined with MYOM2-rs2294066 precisely predicts anti-TNF response in ankylosing spondylitis
por: Liu, Jing, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_94093pg924sv7ocffq3gi8efe9