Cargando…

PinX1 Is a Potential Prognostic Factor for Non-Small-Cell Lung Cancer and Inhibits Cell Proliferation and Migration

PinX1 has been identified as a suppressor of telomerase enzymatic activity. However, the tumour-suppressive roles of PinX1 in different types of human cancers are unclear. PinX1 expression status and its correlation with clinicopathological features in non-small-cell lung cancer (NSCLC) have not bee...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Shengguang, Zhang, Hua, Zhu, Jianquan, Li, Chenguang, Zhu, Jinfang, Shi, Bowen, Zhang, Bin, Wang, Changli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549499/ https://www.ncbi.nlm.nih.gov/pubmed/28815183 http://dx.doi.org/10.1155/2017/7956437

Ejemplares similares

PinX1t, a Novel PinX1 Transcript Variant, Positively Regulates Cardiogenesis of Embryonic Stem Cells
por: Chan, Hing Chung, et al.
Publicado: (2020)

Nucleophosmin Interacts with PIN2/TERF1-interacting Telomerase Inhibitor 1 (PinX1) and Attenuates the PinX1 Inhibition on Telomerase Activity
por: Cheung, Derek Hang-Cheong, et al.
Publicado: (2017)

PinX1 regulation of telomerase activity and apoptosis in nasopharyngeal carcinoma cells
por: Lai, Xiao-Fen, et al.
Publicado: (2012)

Increased Stability of Nucleolar PinX1 in the Presence of TERT
por: Keo, Ponnarath, et al.
Publicado: (2015)

PinX1: structure, regulation and its functions in cancer
por: Li, Hai-Long, et al.
Publicado: (2016)

Hesperidin Inhibits Lung Cancer In Vitro and In Vivo Through PinX1
por: Yao, Yang, et al.
Publicado: (2022)

Selective killing of Burkitt's lymphoma cells by mBAFF-targeted delivery of PinX1
por: Zhang, L, et al.
Publicado: (2011)

The depletion of PinX1 involved in the tumorigenesis of non-small cell lung cancer promotes cell proliferation via p15/cyclin D1 pathway
por: Tian, Xiao-Peng, et al.
Publicado: (2017)

Low expression of PinX1 is associated with malignant behavior in basal-like breast cancer
por: Feng, Yu-Zhen, et al.
Publicado: (2017)

Expression of FOXC2, PinX1, Ki-67 and Cyclin D1 in cutaneous cell carcinoma
por: Zhao, Haiying, et al.
Publicado: (2017)

Reduced expression of PinX1 correlates to progressive features in patients with prostate cancer
por: Shi, Rong, et al.
Publicado: (2014)

PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathway
por: Liu, Jian-Ye, et al.
Publicado: (2013)

The PinX1/NPM interaction associates with hTERT in early-S phase and facilitates telomerase activation
por: Ho, Sai-Tim, et al.
Publicado: (2019)

PinX1 suppresses tumorigenesis by negatively regulating telomerase/telomeres in colorectal carcinoma cells and is a promising molecular marker for patient prognosis
por: Qian, Dong, et al.
Publicado: (2016)

PinX1-siRNA/mPEG-PEI-SPION combined with doxorubicin enhances the inhibition of glioma growth
por: LONG, LING, et al.
Publicado: (2014)

PinX1: a sought-after major tumor suppressor at human chromosome 8p23
por: Zhou, Xiao Zhen
Publicado: (2011)

Prognostic value of number of negative lymph node in patients with stage II and IIIa non-small cell lung cancer
por: Wang, Shengguang, et al.
Publicado: (2017)

Pin2 telomeric repeat factor 1-interacting telomerase inhibitor 1 (PinX1) inhibits nasopharyngeal cancer cell stemness: implication for cancer progression and therapeutic targeting
por: Yu, Chaosheng, et al.
Publicado: (2020)

Genetic profile and biological implication of PIN2/TRF1-interacting telomerase inhibitor 1 (PinX1) in human cancers: an analysis using The Cancer Genome Atlas
por: Huang, Wei-Juan, et al.
Publicado: (2017)

The Role of PinX1 in Growth Control of Breast Cancer Cells and Its Potential Molecular Mechanism by mRNA and lncRNA Expression Profiles Screening
por: Shi, Rong, et al.
Publicado: (2014)

UTP14A, DKC1, DDX10, PinX1, and ESF1 Modulate Cardiac Angiogenesis Leading to Obesity-Induced Cardiac Injury
por: Pan, Xiaoyu, et al.
Publicado: (2022)

Prognostic Value Analysis of Mutational and Clinicopathological Factors in Non-Small Cell Lung Cancer
por: Li, Chenguang, et al.
Publicado: (2014)

PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway
por: Shi, Meilin, et al.
Publicado: (2015)

Prognostic significance of combined fibrinogen concentration and neutrophil-to-lymphocyte ratio in patients with resectable non-small cell lung cancer
por: Huang, Wuhao, et al.
Publicado: (2018)

PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-κB-dependent transcription
por: Li, Hai-Long, et al.
Publicado: (2015)

Prognostic Significance of Combination of Preoperative Platelet Count and Neutrophil-Lymphocyte Ratio (COP-NLR) in Patients with Non-Small Cell Lung Cancer: Based on a Large Cohort Study
por: Zhang, Hua, et al.
Publicado: (2015)

Prognostic and Clinicopathological Value of PINX1 in Various Human Tumors: A Meta-Analysis
por: Liang, Hao, et al.
Publicado: (2018)

The prognostic value of the preoperative albumin to alkaline phosphatase ratio in patients with non‐small cell lung cancer after surgery
por: Zhang, Lianmin, et al.
Publicado: (2019)

Kras mutations increase telomerase activity and targeting telomerase is a promising therapeutic strategy for Kras-mutant NSCLC
por: Liu, Weiran, et al.
Publicado: (2016)

Association between the PINX1 and NAT2 polymorphisms and serum lipid levels
por: Zhang, Qing-Hui, et al.
Publicado: (2017)

Gambogenic acid inhibits the proliferation of small-cell lung cancer cells by arresting the cell cycle and inducing apoptosis
por: Huang, Tingting, et al.
Publicado: (2019)

Bioinformatic analysis of PLOD family member expression and prognostic value in non-small cell lung cancer
por: Qi, Qi, et al.
Publicado: (2021)

Hyperglycemia induces gastric carcinoma proliferation and migration via the Pin1/BRD4 pathway
por: Yu, Jianjian, et al.
Publicado: (2022)

Association of the PINX1 Variant rs6984094, Which Lengthens Telomeres, with Systemic Lupus Erythematosus Susceptibility in Chinese Populations
por: Qi, Yuan-yuan, et al.
Publicado: (2021)

Pin1 coordinates HDAC6 upregulation with cell migration in lung cancer cells
por: Chuang, Hsiang-Hao, et al.
Publicado: (2020)

Distinct Prognostic Values of Alcohol Dehydrogenase Family Members for Non-Small Cell Lung Cancer
por: Wang, Peng, et al.
Publicado: (2018)

Simvastatin Suppresses Proliferation and Migration in Non-small Cell Lung Cancer via Pyroptosis
por: Wang, Fengjiao, et al.
Publicado: (2018)

Calponin 3 suppresses proliferation, migration and invasion of non-small cell lung cancer cells
por: Yang, Chenglin, et al.
Publicado: (2021)

TIPE3 differentially modulates proliferation and migration of human non-small-cell lung cancer cells via distinct subcellular location
por: Wang, Guannan, et al.
Publicado: (2018)

miR-491-5p inhibits the proliferation and migration of A549 cells by FOXP4
por: Wu, Fuyong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_iboie5lrjhm2ckkpt0l3hjhl2f