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Regenerating Family Member 4 (Reg4) Enhances 5-Fluorouracil Resistance of Gastric Cancer Through Activating MAPK/Erk/Bim Signaling Pathway

BACKGROUND: Reg4, a member of the Reg multigene family, is highly upregulated in many gastrointestinal cancers including gastric cancer (GC). The enhanced expression of Reg4 is associated with the resistance of GC to 5-fluorouracil (5-FU), while the underlying mechanism is not clear. The aim of the...

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Detalles Bibliográficos
Autores principales:	Jin, Jiaoyue, Lv, Hang, Wu, Junzhou, Li, Dan, Chen, Kaiyan, Zhang, Fanrong, Han, Jing, Feng, Jianguo, Zhang, Nan, Yu, Herbert, Su, Dan, Ying, Lisha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549713/ https://www.ncbi.nlm.nih.gov/pubmed/28759561 http://dx.doi.org/10.12659/MSM.903134

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