Trans-acting epigenetic effects of chromosomal aneuploidies: lessons from Down syndrome and mouse models

An important line of postgenomic research seeks to understand how genetic factors can influence epigenetic patterning. Here we review epigenetic effects of chromosomal aneuploidies, focusing on findings in Down syndrome (DS, trisomy 21). Recent work in human DS and mouse models has shown that the ex...

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Detalles Bibliográficos
Autores principales: Do, Catherine, Xing, Zhuo, Yu, Y Eugene, Tycko, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549717/
https://www.ncbi.nlm.nih.gov/pubmed/27911079
http://dx.doi.org/10.2217/epi-2016-0138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549717/
https://www.ncbi.nlm.nih.gov/pubmed/27911079
http://dx.doi.org/10.2217/epi-2016-0138

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